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Basil J Nikolau

Explore the profile of Basil J Nikolau including associated specialties, affiliations and a list of published articles. Areas
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Articles 97
Citations 2080
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Recent Articles
1.
Wang L, Foster C, Mentzen W, Tanvir R, Meng Y, Nikolau B, et al.
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39409177
The starch metabolic network was investigated in relation to other metabolic processes by examining a mutant with altered single-gene expression of ATP citrate lyase (ACL), an enzyme responsible for generating...
2.
Alexander L, Winkelman D, Stenback K, Lane M, Campbell K, Trost E, et al.
Front Plant Sci . 2024 Jul; 15:1403779. PMID: 39055356
The maize and genes are homologs, which encode proteins that belong to the BAHD family of acyltransferases. genetic studies have demonstrated that these genes may be involved in the elongation...
3.
Chen K, Bhunia R, Wendt M, Campidilli G, McNinch C, Hassan A, et al.
J Exp Bot . 2024 Jul; 75(20):6500-6522. PMID: 39031128
The plant cuticle is a complex extracellular lipid barrier that has multiple protective functions. This study investigated cuticle deposition by integrating metabolomics and transcriptomics data gathered from six different maize...
4.
Jing F, Chen K, Yandeau-Nelson M, Nikolau B
Front Bioeng Biotechnol . 2024 Apr; 12:1379121. PMID: 38665811
Modulating the catalytic activity of acyl-ACP thioesterase (TE) is an important biotechnological target for effectively increasing flux and diversifying products of the fatty acid biosynthesis pathway. In this study, a...
5.
Chen K, Alexander L, Mahgoub U, Okazaki Y, Higashi Y, Perera A, et al.
Plant Physiol . 2024 Mar; 195(3):2234-2255. PMID: 38537616
The hydrophobic cuticle is the first line of defense between aerial portions of plants and the external environment. On maize (Zea mays L.) silks, the cuticular cutin matrix is infused...
6.
Haltom J, Trovao N, Guarnieri J, Vincent P, Singh U, Tsoy S, et al.
medRxiv . 2023 Dec; PMID: 38076862
The orphan gene of SARS-CoV-2, ORF10, is the least studied gene in the virus responsible for the COVID-19 pandemic. Recent experimentation indicated ORF10 expression moderates innate immunity in vitro. However,...
7.
Cook T, Isenegger D, Dutta S, Sahab S, Kay P, Aboobucker S, et al.
Front Plant Sci . 2023 Jun; 14:1204813. PMID: 37332695
Efforts to increase genetic gains in breeding programs of flowering plants depend on making genetic crosses. Time to flowering, which can take months to decades depending on the species, can...
8.
Wang L, Tonsager A, Zheng W, Wang Y, Stessman D, Fang W, et al.
Front Plant Sci . 2023 Apr; 14:1126139. PMID: 37051080
We demonstrate two synthetic single-cell systems that can be used to better understand how the acquisition of an orphan gene can affect complex phenotypes. The Arabidopsis orphan gene, () has...
9.
Sofeo N, Winkelman D, Leung K, Nikolau B
Front Mol Biosci . 2023 Apr; 10:1117921. PMID: 37006614
Acetyl-CoA synthetase (ACS) is one of several enzymes that generate the key metabolic intermediate, acetyl-CoA. In microbes and mammals ACS activity is regulated by the post-translational acetylation of a key...
10.
Ding G, Mugume Y, Duenas M, Lee Y, Liu M, Nettleton D, et al.
Front Plant Sci . 2023 Mar; 14:1093358. PMID: 36875559
Research strategies that combine molecular data from multiple levels of genome expression (i.e., multi-omics data), often referred to as a systems biology strategy, has been advocated as a route to...