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Fuming Zhang

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Articles 392
Citations 6364
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Recent Articles
21.
He P, Song Y, Jin W, Li Y, Xia K, Kim S, et al.
Glycoconj J . 2024 Apr; 41(2):163-174. PMID: 38642280
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide COVID-19 pandemic, leading to 6.8 million deaths. Numerous variants have emerged since its outbreak, resulting in its significantly...
22.
Gandy L, Zhang F, Xu D, Pedersen L, Grobe K, Wang C
Front Mol Biosci . 2024 Apr; 11:1386623. PMID: 38572447
No abstract available.
23.
Jin W, Zhang F, Linhardt R
Syst Microbiol Biomanuf . 2024 Mar; 1(2):123-130. PMID: 38524245
Glycosaminoglycans (GAGs) are a class of linear polysaccharides, consisting of alternating disaccharide sequences of uronic acid and hexosamines (or galactose) with and without sulfation. They can interact with various proteins,...
24.
Douaisi M, Paskaleva E, Fu L, Grover N, McManaman C, Varghese S, et al.
Proc Natl Acad Sci U S A . 2024 Mar; 121(14):e2315586121. PMID: 38498726
Heparins have been invaluable therapeutic anticoagulant polysaccharides for over a century, whether used as unfractionated heparin or as low molecular weight heparin (LMWH) derivatives. However, heparin production by extraction from...
25.
Wei C, Shi M, Wang Z, Lan W, Feng N, Zhang F, et al.
J Ethnopharmacol . 2024 Mar; 327:118039. PMID: 38479545
Ethnopharmacological Relevance: The anti-tumor related diseases of Coptidis Rhizoma (Huanglian) were correlated with its traditional use of removing damp-heat, clearing internal fire, and counteracting toxicity. In the recent years, Coptidis...
26.
Yang J, Song Y, Jin W, Xia K, Burnett G, Qiao W, et al.
Viruses . 2024 Feb; 16(2). PMID: 38400013
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells. Owing...
27.
Cao M, Bian X, Ji Z, Sohail M, Zhang F, Linhardt R, et al.
Anal Chem . 2024 Feb; 96(9):3970-3978. PMID: 38386411
Heparin is a highly sulfated linear glycosaminoglycan that is used as an anticoagulant to prevent and treat thrombotic diseases. Herein, we find that heparin specifically inhibits the activation of the...
28.
Chen Q, Xu X, Xie S, Sheng A, Han N, Tian Z, et al.
Carbohydr Polym . 2024 Feb; 330:121834. PMID: 38368111
Endothelial dysfunction induced by oxidative stress is an early predictor of atherosclerosis, which can cause various cardiovascular diseases. The glycocalyx layer on the endothelial cell surface acts as a barrier...
29.
Sun B, Zou K, Zhao Y, Tang Y, Zhang F, Chen W, et al.
Front Microbiol . 2024 Jan; 14:1301065. PMID: 38169798
Introduction: Proteases exhibit a wide range of applications, and among them, alkaline proteases have become a prominent area of research due to their stability in highly alkaline environments. To optimize...
30.
Oshima K, Siddiqui N, Orfila J, Carter D, Laing J, Han X, et al.
Matrix Biol . 2023 Dec; 125:88-99. PMID: 38135163
Traumatic brain injury (TBI) is the leading cause of death and disability due to injury worldwide. Extracellular matrix (ECM) remodeling is known to significantly contribute to TBI pathophysiology. Glycosaminoglycans, which...