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Frederik Dagnaes-Hansen

Explore the profile of Frederik Dagnaes-Hansen including associated specialties, affiliations and a list of published articles. Areas
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Articles 99
Citations 2726
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Recent Articles
1.
Smith A, Zuwala K, Pilgram O, Johansen K, Tolstrup M, Dagnaes-Hansen F, et al.
ACS Macro Lett . 2022 Jun; 5(10):1089-1094. PMID: 35658186
Albumin is an exquisite tool of nature used in biomedicine to achieve long blood residence time for drugs, but the payload it can carry is typically limited to one molecule...
2.
Riber C, Andersen A, Rolskov L, Zuwala K, Gajda P, Lovschall K, et al.
ACS Macro Lett . 2022 Jun; 6(9):935-940. PMID: 35650894
Synthetic polymers make strong contributions as tools for delivery of biological drugs and chemotherapeutics. The most praised characteristic of polymers in these applications is complete lack of pharmacological function such...
3.
Andersen A, Riber C, Zuwala K, Tolstrup M, Dagnaes-Hansen F, Denton P, et al.
ACS Macro Lett . 2022 May; 7(5):587-591. PMID: 35632936
Antiretroviral therapy (ART) has revolutionized HIV treatment, yet grand challenges remain: (i) short blood and body residence time of the antiviral drugs, (ii) relative poor antiretroviral drug penetrance into key...
4.
Ahring K, Dagnaes-Hansen F, Bruel A, Christensen M, Jensen E, Jensen T, et al.
PLoS One . 2022 Jan; 17(1):e0261150. PMID: 35015767
Introduction: Management of phenylketonuria (PKU) is mainly achieved through dietary control with limited intake of phenylalanine (Phe) from food, supplemented with low protein (LP) food and a mixture of free...
5.
Berthelsen M, Riedel M, Cai H, Skaarup S, Alstrup A, Dagnaes-Hansen F, et al.
Cancers (Basel) . 2021 Jul; 13(12). PMID: 34208747
The generation of large transgenic animals is impeded by complex cloning, long maturation and gastrulation times. An introduction of multiple gene alterations increases the complexity. We have cloned a transgenic...
6.
Haldrup J, Strand S, Cieza-Borrella C, Jakobsson M, Riedel M, Norgaard M, et al.
Oncogene . 2020 Nov; 40(4):763-776. PMID: 33249427
Available tools for prostate cancer (PC) prognosis are suboptimal but may be improved by better knowledge about genes driving tumor aggressiveness. Here, we identified FRMD6 (FERM domain-containing protein 6) as...
7.
Larsen M, Mandrup O, Schelde K, Luo Y, Sorensen K, Dagnaes-Hansen F, et al.
J Control Release . 2020 Mar; 322:53-63. PMID: 32145268
Albumin accumulation in tumours could reflect a role of albumin in transport of endogenous nutrient cargos required for cellular growth and not just a suggested source of amino acids; a...
8.
Jarlstad Olesen M, Walther R, Poier P, Dagnaes-Hansen F, Zelikin A
Angew Chem Int Ed Engl . 2020 Feb; 59(19):7390-7396. PMID: 32073708
In this work, a tumor growth intervention by localized drug synthesis within the tumor volume, using the enzymatic repertoire of the tumor itself, is presented. Towards the overall success, molecular,...
9.
Andersen A, Nielsen S, Olesen R, Mack K, Dagnaes-Hansen F, Uldbjerg N, et al.
J Vis Exp . 2020 Feb; (155). PMID: 32065160
Humanized mice provide a sophisticated platform to study human immunodeficiency virus (HIV) virology and to test antiviral drugs. This protocol describes the establishment of a human immune system in adult...
10.
Vu-Quang H, Vinding M, Jakobsen M, Song P, Dagnaes-Hansen F, Nielsen N, et al.
Sci Rep . 2019 Oct; 9(1):14314. PMID: 31586092
Rheumatoid arthritis (RA) is an autoimmune disease that causes pain and tissue destruction in people worldwide. An accurate diagnosis is paramount in order to develop an effective treatment plan. This...