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Frederic Sierro

Explore the profile of Frederic Sierro including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 2538
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Recent Articles
1.
Howell N, Middleton R, Sierro F, Fraser B, Wyatt N, Chacon A, et al.
Int J Radiat Oncol Biol Phys . 2024 Mar; 120(1):229-242. PMID: 38479560
Purpose: Neutron capture enhanced particle therapy (NCEPT) is a proposed augmentation of charged particle therapy that exploits thermal neutrons generated internally, within the treatment volume via nuclear fragmentation, to deliver...
2.
English K, Tan S, Kwan R, Holz L, Sierro F, McGuffog C, et al.
Immunol Cell Biol . 2022 Jun; 100(6):394-408. PMID: 35718354
Portal tracts are key intrahepatic structures where leukocytes accumulate during immune responses. They contain the blood inflow, which includes portal blood from the gut, and lymphatic and biliary outflow of...
3.
Hewavisenti R, Ferguson A, Gasparini G, Ohashi T, Braun A, Watkins T, et al.
Immunol Cell Biol . 2021 Jun; 99(8):894-906. PMID: 34080230
Regulatory T cells (Tregs) play a critical role in immune regulation and peripheral tolerance. While different types of Tregs have been identified in both mice and humans, much of our...
4.
McDonough L, Meredith K, Nikagolla C, Middleton R, Tan J, Ranasinghe A, et al.
Sci Rep . 2020 Oct; 10(1):18295. PMID: 33106529
Chronic kidney disease (CKD) of unknown etiology (CKDu) mostly affects agricultural communities in Central America, South Asia, Africa, but likely also in North America and Australia. One such area with...
5.
Pinget G, Tan J, Janac B, Kaakoush N, Angelatos A, OSullivan J, et al.
Front Nutr . 2019 Jul; 6:100. PMID: 31334242
[This corrects the article DOI: 10.3389/fnut.2019.00057.].
6.
Pinget G, Tan J, Janac B, Kaakoush N, Angelatos A, OSullivan J, et al.
Front Nutr . 2019 Jun; 6:57. PMID: 31165072
The interaction between gut microbiota and host plays a central role in health. Dysbiosis, detrimental changes in gut microbiota and inflammation have been reported in non-communicable diseases. While diet has...
7.
Sierro F, Grau G
Front Immunol . 2019 May; 10:830. PMID: 31057552
Complications from malaria parasite infections still cost the lives of close to half a million people every year. The most severe is cerebral malaria (CM). Employing murine models of CM,...
8.
Florido M, Muflihah H, Lin L, Xia Y, Sierro F, Palendira M, et al.
Mucosal Immunol . 2018 Aug; 11(6):1743-1752. PMID: 30115996
The lung is the primary site of infection with the major human pathogen, Mycobacterium tuberculosis. Effective vaccines against M. tuberculosis must stimulate memory T cells to provide early protection in...
9.
Sheu A, Chan Y, Ferguson A, Bakhtyari M, Hawke W, White C, et al.
Diabetologia . 2018 Apr; 61(7):1633-1643. PMID: 29691600
Aims/hypothesis: Numerous adaptations of the maternal immune system are necessary during pregnancy to maintain immunological tolerance to the semi-allogeneic fetus. Several complications of pregnancy have been associated with dysregulation of...
10.
Sierro F, Evrard M, Rizzetto S, Melino M, Mitchell A, Florido M, et al.
Immunity . 2017 Aug; 47(2):374-388.e6. PMID: 28813662
The liver is positioned at the interface between two routes traversed by pathogens in disseminating infection. Whereas blood-borne pathogens are efficiently cleared in hepatic sinusoids by Kupffer cells (KCs), it...