Geoffrey W McCaughan
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Explore the profile of Geoffrey W McCaughan including associated specialties, affiliations and a list of published articles.
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231
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4019
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Recent Articles
1.
Gomez-Orellana A, Rodriguez-Peralvarez M, Guijo-Rubio D, Gutierrez P, Majumdar A, McCaughan G, et al.
Clin Gastroenterol Hepatol
. 2025 Jan;
PMID: 39848457
Background & Aims: We aimed to develop and validate an artificial intelligence score (gender-equity model for liver allocation using artificial intelligence [GEMA-AI]) to predict liver transplantation (LT) waiting list outcomes...
2.
Chin S, Kench C, Cao R, Lee C, Waller K, Virtue S, et al.
Intern Med J
. 2025 Jan;
PMID: 39804035
Background: Access to liver transplantation (LT) is affected by geographic disparities. Higher waitlist mortality is observed in patients residing farther from LT centres, but the impact of distance on post-LT...
3.
Marsh-Wakefield F, Santhakumar C, Ferguson A, Ashhurst T, Shin J, Guan F, et al.
Hepatol Commun
. 2025 Jan;
8(11.
PMID: 39761010
Background: HCC develops in the context of chronic inflammation; however, the opposing roles the immune system plays in both the development and control of tumors are not fully understood. Mapping...
4.
Prince D, Hoque S, Kim C, Maher S, Miller J, Chomley P, et al.
J Gastroenterol Hepatol
. 2024 Oct;
40(1):250-257.
PMID: 39444308
Background And Aim: Most patients with cirrhosis have compensated disease and are cared for in primary care; however, the exact epidemiology within Australia remains largely unknown. The aim of this...
5.
Chen J, Liu K, Vadas M, Gamble J, McCaughan G
Cells
. 2024 Aug;
13(15.
PMID: 39120319
Hepatocellular carcinoma (HCC) is the fourth-leading cause of cancer-related death worldwide. Due to the high mortality rate in HCC patients, discovering and developing novel systemic treatment options for HCC is...
6.
Ly M, Lau N, Dennis C, Chen J, Risbey C, Tan S, et al.
Am J Transplant
. 2024 Jul;
25(1):60-71.
PMID: 39059585
Bile duct regeneration is hypothesized to prevent biliary strictures, a leading cause of morbidity after liver transplantation. Assessing the capacity for biliary regeneration may identify grafts as suitable for transplantation...
7.
Prince D, Hoque S, Kim C, Maher S, Miller J, Chomley P, et al.
Hepatol Commun
. 2024 Jun;
8(7).
PMID: 38934697
Background: Identifying patients with undiagnosed advanced chronic liver disease (ACLD) is a public health challenge. Patients with advanced fibrosis or compensated cirrhosis have much better outcomes than those with decompensated...
8.
Tang L, Chetwood J, Lai M, Yip T, Cao R, Powter E, et al.
Liver Transpl
. 2024 Apr;
30(10):1039-1049.
PMID: 38647419
Acute allograft rejection is a well-known complication of liver transplantation (LT). The incidence, epidemiology, and outcomes of acute rejection have not been well described in Australia. We retrospectively studied consecutive...
9.
Cabanes-Creus M, Liao S, Navarro R, Knight M, Nazareth D, Lau N, et al.
Nat Commun
. 2024 Mar;
15(1):1876.
PMID: 38485924
Developing clinically predictive model systems for evaluating gene transfer and gene editing technologies has become increasingly important in the era of personalized medicine. Liver-directed gene therapies present a unique challenge...
10.
English K, Kwan R, Holz L, McGuffog C, Krol J, Kempe D, et al.
Nat Commun
. 2024 Feb;
15(1):1261.
PMID: 38341416
While CD4 T cells are a prerequisite for CD8 T cell-mediated protection against intracellular hepatotropic pathogens, the mechanisms facilitating the transfer of CD4-help to intrahepatic CD8 T cells are unknown....