Frederic Duconge
Overview
Explore the profile of Frederic Duconge including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
586
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Recent Articles
1.
Bouvier-Muller A, Fourmy D, Fenyi A, Bousset L, Melki R, Duconge F
Nucleic Acids Res
. 2024 Jun;
52(14):8072-8085.
PMID: 38917326
Synucleinopathies, including dementia with Lewy bodies (DLB), Parkinson's disease (PD), and multiple system atrophy (MSA), are characterized by the presence of α-synuclein (α-syn) aggregates in the central nervous system. Recent...
2.
Le Dortz L, Rouxel C, Leroy Q, Duconge F, Boulouis H, Haddad N, et al.
Sci Rep
. 2024 Jan;
14(1):2465.
PMID: 38291133
A. phagocytophilum is a zoonotic and tick-borne bacterium, threatening human and animal health. Many questions persist concerning the variability of strains and the mechanisms governing the interactions with its different...
3.
Zimbres F, Merino E, Butschek G, Butler J, Duconge F, Cassera M
Molecules
. 2024 Jan;
29(1).
PMID: 38202761
Dolichols are isoprenoid end-products of the mevalonate and 2-methyl-D-erythritol-4-phosphate pathways. The synthesis of dolichols is initiated with the addition of several molecules of isopentenyl diphosphate to farnesyl diphosphate. This reaction...
4.
Zutterling C, Todeschini A, Fourmy D, Busso D, Veaute X, Duconge F, et al.
Nucleic Acids Res
. 2023 Nov;
51(22):12367-12380.
PMID: 37933840
Transcription factors contain a DNA-binding domain ensuring specific recognition of DNA target sequences. The family of forkhead (FOX) transcription factors is composed of dozens of paralogs in mammals. The forkhead...
5.
Hanzek A, Duconge F, Siatka C, Duc A
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672400
Ovarian cancer is the deadliest gynecological cancer. With non-specific symptoms of the disease and the lack of effective diagnostic methods, late diagnosis remains the crucial hurdle of the poor prognosis....
6.
Duconge F
Methods Mol Biol
. 2022 Sep;
2570:85-102.
PMID: 36156776
Although SELEX can identify high-affinity aptamers, Doped-SELEX is often performed post-selection for the identification of better variants. Starting from a partially randomized (doped) library derived from an already identified aptamer,...
7.
Alliot J, Theodorou I, Duconge F, Gravel E, Doris E
Chem Commun (Camb)
. 2019 Nov;
55(99):14968-14971.
PMID: 31776519
Micelle-forming amphiphilic drug conjugates were synthesized starting from a biologically active epipodophyllotoxin derivative which was covalently inserted in between a hydrophilic targeting spermine unit, and a hydrophobic stearyl chain. The...
8.
Orefice N, Souchet B, Braudeau J, Alves S, Piguet F, Collaud F, et al.
Mol Ther Methods Clin Dev
. 2019 Aug;
14:237-251.
PMID: 31440523
Exosomes represent a strategy for optimizing the adeno-associated virus (AAV) toward the development of novel therapeutic options for neurodegenerative disorders. However, spreading of exosomes and AAVs after intracerebral administration is...
9.
Alliot J, Theodorou I, Nguyen D, Forier C, Duconge F, Gravel E, et al.
Nanoscale
. 2019 May;
11(19):9756-9759.
PMID: 31066425
Micelle-forming amphiphilic drug conjugates were synthesized starting from a biologically active epipodophyllotoxin derivative which was covalently inserted in between a hydrophilic PEG unit and a hydrophobic stearyl chain. The epipodophyllotoxin-containing...
10.
Doerflinger A, Nguyen Quang N, Gravel E, Duconge F, Doris E
Int J Pharm
. 2019 Apr;
565:59-63.
PMID: 31029658
In this study, a "click and hybridization" strategy was developed for the functionalization of polydiacetylene micelles with a targeting aptamer ligand. Decoration of the nanocarriers with an anti-Annexin A2 sequence...