Frederic Charron
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Explore the profile of Frederic Charron including associated specialties, affiliations and a list of published articles.
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Articles
63
Citations
2770
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Recent Articles
1.
Balekoglu N, Michaud J, Sauve R, Ayinde K, Lin S, Liu Y, et al.
iScience
. 2024 Dec;
27(12):111333.
PMID: 39640588
During development, Shh attracts axons of spinal cord commissural neurons to the floor plate. Shh-mediated attraction of commissural axons requires the receptor Boc. How Boc regulates cytoskeletal changes in growth...
2.
Chaudhari K, Zhang K, Yam P, Zang Y, Kramer D, Gagnon S, et al.
Sci Signal
. 2024 Oct;
17(856):eadk2345.
PMID: 39353037
The axon guidance cue netrin-1 signals through its receptor DCC (deleted in colorectal cancer) to attract commissural axons to the midline. Variants in DCC are frequently associated with congenital mirror...
3.
Sauve R, Morin S, Yam P, Charron F
J Neurosci
. 2024 Jun;
44(30.
PMID: 38886055
During nervous system development, Sonic hedgehog (Shh) guides developing commissural axons toward the floor plate of the spinal cord. To guide axons, Shh binds to its receptor Boc and activates...
4.
Liu X, Yam P, Schlienger S, Cai E, Zhang J, Chen W, et al.
Nat Commun
. 2024 Apr;
15(1):3365.
PMID: 38664376
Hedgehog (Hh) signaling relies on the primary cilium, a cell surface organelle that serves as a signaling hub for the cell. Using proximity labeling and quantitative proteomics, we identify Numb...
5.
Collins Hutchinson M, St-Onge J, Schlienger S, Boudrahem-Addour N, Mougharbel L, Michaud J, et al.
Mov Disord
. 2024 Feb;
39(2):400-410.
PMID: 38314870
Background: Congenital mirror movements (CMM) is a rare neurodevelopmental disorder characterized by involuntary movements from one side of the body that mirror voluntary movements on the opposite side. To date,...
6.
Schlienger S, Yam P, Balekoglu N, Ducuing H, Michaud J, Makihara S, et al.
Sci Adv
. 2023 May;
9(19):eadd5501.
PMID: 37172092
Mirror movements (MM) disorder is characterized by involuntary movements on one side of the body that mirror intentional movements on the opposite side. We performed genetic characterization of a family...
7.
Ruiz de Almodovar C, Fabre P, Knevels E, Coulon C, Segura I, Haddick P, et al.
Neuron
. 2023 Apr;
111(8):1348.
PMID: 37080170
No abstract available.
8.
Tamayo-Orrego L, Gallo D, Racicot F, Bemmo A, Mohan S, Ho B, et al.
Nat Cancer
. 2022 Apr;
2(5):575.
PMID: 35430602
No abstract available.
9.
Tamayo-Orrego L, Gallo D, Racicot F, Bemmo A, Mohan S, Ho B, et al.
Nat Cancer
. 2022 Feb;
1(8):840-854.
PMID: 35122047
The mechanisms generating cancer-initiating mutations are not well understood. Sonic hedgehog (SHH) pathway activation is frequent in medulloblastoma (MB), with PTCH1 mutations being a common initiating event. Here we investigated...
10.
Thiry L, Lemaire C, Rastqar A, Lemieux M, Peng J, Ferent J, et al.
eNeuro
. 2022 Feb;
9(2).
PMID: 35115383
Axon guidance receptors such as deleted in colorectal cancer (DCC) contribute to the normal formation of neural circuits, and their mutations can be associated with neural defects. In humans, heterozygous...