Frederic Charron
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Explore the profile of Frederic Charron including associated specialties, affiliations and a list of published articles.
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63
Citations
2770
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Recent Articles
11.
Ferent J, Constable S, Gigante E, Yam P, Mariani L, Legue E, et al.
Cell Rep
. 2019 Dec;
29(11):3356-3366.e3.
PMID: 31825820
The small GTPase Arl13b is enriched in primary cilia and regulates Sonic hedgehog (Shh) signaling. During neural development, Shh controls patterning and proliferation through a canonical, transcription-dependent pathway that requires...
12.
Tamayo-Orrego L, Charron F
F1000Res
. 2019 Nov;
8.
PMID: 31700613
Medulloblastoma, the most common of the malignant pediatric brain tumors, is a group of four molecularly and clinically distinct cancers with different cells of origin. One of these medulloblastoma groups...
13.
14.
Accogli A, Calabretta S, St-Onge J, Boudrahem-Addour N, Dionne-Laporte A, Joset P, et al.
Am J Hum Genet
. 2019 Oct;
105(4):854-868.
PMID: 31585109
Cadherins constitute a family of transmembrane proteins that mediate calcium-dependent cell-cell adhesion. The extracellular domain of cadherins consists of extracellular cadherin (EC) domains, separated by calcium binding sites. The EC...
15.
Ferent J, Giguere F, Jolicoeur C, Morin S, Michaud J, Makihara S, et al.
Neuron
. 2019 May;
102(6):1157-1171.e5.
PMID: 31054872
During development, Shh attracts commissural axons toward the floor plate through a non-canonical, transcription-independent signaling pathway that requires the receptor Boc. Here, we find that Shh induces Boc internalization into...
16.
Zakaria M, Ferent J, Hristovska I, Laouarem Y, Zahaf A, Kassoussi A, et al.
Development
. 2019 May;
146(9).
PMID: 31048318
Myelination leads to the formation of myelin sheaths surrounding neuronal axons and is crucial for function, plasticity and repair of the central nervous system (CNS). It relies on the interaction...
17.
Wu Z, Makihara S, Yam P, Teo S, Renier N, Balekoglu N, et al.
Neuron
. 2019 Jan;
101(4):635-647.e4.
PMID: 30661738
An important model for axon pathfinding is provided by guidance of embryonic commissural axons from dorsal spinal cord to ventral midline floor plate (FP). FP cells produce a chemoattractive activity,...
18.
Brennan-Crispi D, Overmiller A, Tamayo-Orrego L, Marous M, Sahu J, McGuinn K, et al.
J Invest Dermatol
. 2018 Oct;
139(2):300-307.
PMID: 30291846
Activation of the hedgehog pathway is causative of virtually all sporadic and Gorlin syndrome-related basal cell carcinomas (BCCs), with loss of function of Ptc1 being the most common genomic lesion....
19.
Makihara S, Morin S, Ferent J, Cote J, Yam P, Charron F
Dev Cell
. 2018 Aug;
46(4):410-425.e7.
PMID: 30078728
In the developing spinal cord, Sonic hedgehog (Shh) attracts commissural axons toward the floorplate. How Shh regulates the cytoskeletal remodeling that underlies growth cone turning is unknown. We found that...
20.
Charron F
Neuron
. 2018 Jul;
99(1):1-2.
PMID: 30001504
In this issue of Neuron, Cagnetta et al. (2018) describe a novel method to identify, in an unbiased manner, newly synthesized axonal proteins in response to axon guidance cues. They...