Annika Spottke
Overview
Explore the profile of Annika Spottke including associated specialties, affiliations and a list of published articles.
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128
Citations
3036
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Recent Articles
1.
Haag L, Lancini E, Yakupov R, Ziegler G, Yi Y, Lusebrink F, et al.
Brain Commun
. 2025 Feb;
7(1):fcaf031.
PMID: 39926613
Neurotransmitter systems of noradrenaline, dopamine, serotonin and acetylcholine are implicated in cognitive functions such as memory, learning and attention and are known to be altered in neurodegenerative diseases like Alzheimer's...
2.
Porsche S, Klietz M, Greten S, Piot I, Jensen I, Wegner F, et al.
Mov Disord Clin Pract
. 2025 Jan;
PMID: 39868903
Background: Patients with Progressive Supranuclear Palsy (PSP) suffer from several neuropsychological impairments. These mainly affect the frontal lobe and subcortical brain structures. However, a scale for the assessment of cognitive...
3.
Schneider L, Freiesleben S, van Breukelen G, Wang X, Brosseron F, Heneka M, et al.
Alzheimers Dement
. 2025 Jan;
21(2):e14545.
PMID: 39868793
Introduction: The beneficial effects of amyloid beta 1-38, or Aβ(1-38), on Alzheimer's disease (AD) progression in humans in vivo remain controversial. We investigated AD patients' cerebrospinal fluid (CSF) Aβ(1-38) and...
4.
Liu K, Betts M, Hammerer D, Duzel E, Mather M, Roiser J, et al.
Brain Commun
. 2025 Jan;
7(1):fcae457.
PMID: 39801712
Hyperphosphorylated tau accumulation is seen in the noradrenergic locus coeruleus from the earliest stages of Alzheimer's disease onwards and has been associated with symptoms of agitation. It is hypothesized that...
5.
Quattrone A, Franzmeier N, Levin J, Petzold G, Spottke A, Brosseron F, et al.
Mov Disord
. 2025 Jan;
PMID: 39797511
Background: The recent Movement Disorders Society (MDS)-progressive supranuclear palsy (PSP) diagnostic criteria conceptualized three clinical diagnostic certainty levels: "suggestive of PSP" for sensitive early diagnosis based on subtle clinical signs,...
6.
Hass S, Liebscher M, Richter A, Fliessbach K, Laske C, Sodenkamp S, et al.
Front Aging Neurosci
. 2025 Jan;
16():1451850.
PMID: 39777046
Background: In humans, environmental enrichment (EE), as measured by the engagement in a variety of leisure activities, has been associated with larger hippocampal structure and better memory function. The present...
7.
Rudolph J, Rueckel J, Dopfert J, Ling W, Opalka J, Brem C, et al.
Alzheimers Dement (Amst)
. 2024 Dec;
16(4):e70037.
PMID: 39665087
Introduction: This study evaluates the clinical value of a deep learning-based artificial intelligence (AI) system that performs rapid brain volumetry with automatic lobe segmentation and age- and sex-adjusted percentile comparisons....
8.
Blomeke L, Rehn F, Pils M, Kraemer-Schulien V, Cousin A, Kutzsche J, et al.
Commun Med (Lond)
. 2024 Dec;
4(1):262.
PMID: 39658587
Background: Quantification of Amyloid beta (Aβ) oligomers in plasma enables early diagnosis of Alzheimer's Disease (AD) and improves our understanding of underlying pathologies. However, quantification necessitates an extremely sensitive and...
9.
Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy E, Bernal J, et al.
Nat Commun
. 2024 Nov;
15(1):9815.
PMID: 39537609
The cognitive reserve (CR) hypothesis posits that individuals can differ in how their brain function is disrupted by pathology associated with aging and neurodegeneration. Here, we test this hypothesis in...
10.
Martinelli F, Heinken A, Henning A, Ulmer M, Hensen T, Gonzalez A, et al.
Sci Rep
. 2024 Nov;
14(1):27692.
PMID: 39532987
No abstract available.