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Franziska Herster

Explore the profile of Franziska Herster including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 237
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Recent Articles
1.
Acker F, Klein A, Rasokat A, Eisert A, Kron A, Christopoulos P, et al.
Clin Lung Cancer . 2024 Aug; 25(8):672-682.e5. PMID: 39153867
Purpose: MET amplification is a common resistance mechanism to EGFR inhibition in EGFR-mutant non-small cell lung cancer (NSCLC). Several trials showed encouraging results with combined EGFR and MET inhibition (EGFRi/METi)....
2.
Christopoulos P, Herster F, Hoffknecht P, Falk M, Tiemann M, Kopp H, et al.
Front Oncol . 2024 May; 14:1347742. PMID: 38769948
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) represent first-line standard of care in unresectable mutation-positive (m+) non-small cell lung cancer (NSCLC). However, 10-20% of patients with m+ NSCLC...
3.
Roggia C, Armeanu-Ebinger S, Gschwind A, Seibel-Kelemen O, Hertler S, Faust U, et al.
Eur J Cancer . 2022 Dec; 179:48-55. PMID: 36495689
Background: Sequencing of tumour tissue with comprehensive gene panels is increasingly used to guide treatment in precision oncology. Analysis of tumour-normal pairs allows in contrast to tumour-only assessment direct discrimination...
4.
Seyfried N, Yurttas C, Burkard M, Oswald B, Tolios A, Herster F, et al.
Cancers (Basel) . 2022 Mar; 14(5). PMID: 35267468
Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) was considered a promising treatment for patients with peritoneal metastasis from colorectal cancer. However, the recently published randomized controlled PRODIGE 7 trial...
5.
Bittner Z, Liu X, Mateo Tortola M, Tapia-Abellan A, Shankar S, Andreeva L, et al.
J Exp Med . 2021 Sep; 218(11). PMID: 34554188
Activity of the NLRP3 inflammasome, a critical mediator of inflammation, is controlled by accessory proteins, posttranslational modifications, cellular localization, and oligomerization. How these factors relate is unclear. We show that...
6.
Herster F, Karbach S, Chatterjee M, Weber A
J Invest Dermatol . 2021 Apr; 141(6):1395-1403. PMID: 33810836
Platelets have long been known as mediators of hemostasis and, more recently, as mediators of thromboinflammation, although their physiopathological role has mostly been investigated in the context of disease of...
7.
Herster F, Bittner Z, Archer N, Dickhofer S, Eisel D, Eigenbrod T, et al.
Nat Commun . 2020 Jan; 11(1):105. PMID: 31913271
Psoriasis is an inflammatory skin disease with strong neutrophil (PMN) infiltration and high levels of the antimicrobial peptide, LL37. LL37 in complex with DNA and RNA is thought to initiate...
8.
Bitschar K, Staudenmaier L, Klink L, Focken J, Sauer B, Fehrenbacher B, et al.
J Invest Dermatol . 2019 Dec; 140(5):1054-1065.e4. PMID: 31857094
Staphylococcus aureus is a facultative pathogen found on skin and nasal surfaces. It is usually absent from the skin of healthy humans but frequently colonizes the skin of patients with...
9.
Herster F, Bittner Z, Codrea M, Archer N, Heister M, Loffler M, et al.
Front Immunol . 2019 Sep; 10:1867. PMID: 31474979
Psoriasis is a frequent systemic inflammatory autoimmune disease characterized primarily by skin lesions with massive infiltration of leukocytes, but frequently also presents with cardiovascular comorbidities. Especially polymorphonuclear neutrophils (PMNs) abundantly...
10.
Hafner A, Kolbe U, Freund I, Castiglia V, Kovarik P, Poth T, et al.
Front Immunol . 2019 Mar; 10:198. PMID: 30846984
is a major human pathogen causing a variety of diseases ranging from common pharyngitis to life-threatening soft tissue infections and sepsis. Microbial nucleic acids, especially bacterial RNA, have recently been...