Franz Narberhaus
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Explore the profile of Franz Narberhaus including associated specialties, affiliations and a list of published articles.
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141
Citations
3135
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Recent Articles
1.
Guanzon D, Pienkoss S, Brandenburg V, Roder J, Scheller D, Dietze A, et al.
Nucleic Acids Res
. 2025 Feb;
53(3).
PMID: 39907110
Bacterial pathogens, such as Yersinia pseudotuberculosis, encounter temperature fluctuations during host infection and upon return to the environment. These temperature shifts impact RNA structures globally. While previous transcriptome-wide studies have...
2.
The role of the essential GTPase ObgE in regulating lipopolysaccharide synthesis in Escherichia coli
Dewachter L, Deckers B, Mares-Mejia I, Louwagie E, Vercauteren S, Matthay P, et al.
Nat Commun
. 2024 Nov;
15(1):9684.
PMID: 39516202
During growth, cells need to synthesize and expand their envelope, a process that requires careful regulation. Here, we show that the GTPase ObgE of E. coli contributes to the regulation...
3.
Kleetz J, Mizza A, Shevyreva I, Welter L, Brocks C, Hemschemeier A, et al.
Appl Environ Microbiol
. 2024 Aug;
90(9):e0059024.
PMID: 39120150
Importance: Understanding the molecular mechanisms of symbiotic nitrogen fixation has important implications for sustainable agriculture. The presence of the phospholipid phosphatidylcholine (PC) in the membrane of rhizobia is critical for...
4.
Moller A, Vazquez-Hernandez M, Kutscher B, Brysch R, Bruckner S, Marino E, et al.
J Biol Chem
. 2024 Mar;
300(4):107143.
PMID: 38458396
A promising yet clinically unexploited antibiotic target in difficult-to-treat Gram-negative bacteria is LpxC, the key enzyme in the biosynthesis of lipopolysaccharides, which are the major constituents of the outer membrane....
5.
Schmidt J, Remme D, Eisfeld J, Brandenburg V, Bille H, Narberhaus F
Mol Microbiol
. 2023 Nov;
121(1):26-39.
PMID: 37985428
Agrobacterium tumefaciens is a plant pathogen, broadly known as the causal agent of the crown gall disease. The soil bacterium is naturally resistant to beta-lactam antibiotics by utilizing the inducible...
6.
Vasilopoulos G, Heflik L, Czolkoss S, Heinrichs F, Kleetz J, Yesilyurt C, et al.
FEBS J
. 2023 Nov;
291(4):705-721.
PMID: 37943159
Phosphatidic acid (PA) is the precursor of most phospholipids like phosphatidylethanolamine, phosphatidylglycerol, and cardiolipin. In bacteria, its biosynthesis begins with the acylation of glycerol-3-phosphate to lysophosphatidic acid (LPA), which is...
7.
Scheller D, Becker F, Wimbert A, Meggers D, Pienkoss S, Twittenhoff C, et al.
PLoS Genet
. 2023 Jul;
19(7):e1010669.
PMID: 37428814
Pathogenic bacteria, such as Yersinia pseudotuberculosis encounter reactive oxygen species (ROS) as one of the first lines of defense in the mammalian host. In return, the bacteria react by mounting...
8.
Bruckner S, Muller F, Schadowski L, Kalle T, Weber S, Marino E, et al.
Microlife
. 2023 Jul;
4:uqad031.
PMID: 37426605
The outer membrane (OM) protects Gram-negative bacteria from harsh environmental conditions and provides intrinsic resistance to many antimicrobial compounds. The asymmetric OM is characterized by phospholipids in the inner leaflet...
9.
Moller A, Bruckner S, Tilg L, Kutscher B, Nowaczyk M, Narberhaus F
Mol Microbiol
. 2022 Dec;
119(1):29-43.
PMID: 36464488
The outer membrane (OM) of Gram-negative bacteria functions as an essential barrier and is characterized by an asymmetric bilayer with lipopolysaccharide (LPS) in the outer leaflet. The enzyme LpxC catalyzes...
10.
Brandenburg V, Narberhaus F, Mosig A
PLoS Comput Biol
. 2022 Jul;
18(7):e1010240.
PMID: 35797361
It is well-established that neural networks can predict or identify structural motifs of non-coding RNAs (ncRNAs). Yet, the neural network based identification of RNA structural motifs is limited by the...