Frank C Nichols
Overview
Explore the profile of Frank C Nichols including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
685
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Recent Articles
1.
Bontempo A, Chirino A, Heidari A, Lugo A, Shindo S, Pastore M, et al.
Microbiol Spectr
. 2024 Aug;
12(10):e0059924.
PMID: 39162507
Importance: The oral microbiome is important in health and disease, and in this study, we addressed the potential role of the oral microbiome in COVID-19 infection. Our studies suggest that...
2.
Ghods S, Muszynski A, Yang H, Seelan R, Mohammadi A, Hilson J, et al.
Front Cell Infect Microbiol
. 2024 Jun;
14:1418651.
PMID: 38933693
Background: This study unveils the intricate functional association between cyclic di-3',5'-adenylic acid (c-di-AMP) signaling, cellular bioenergetics, and the regulation of lipopolysaccharide (LPS) profile in , a Gram-negative obligate anaerobe considered...
3.
Bontempo A, Chirino A, Heidari A, Lugo A, Shindo S, Pastore M, et al.
bioRxiv
. 2024 Mar;
PMID: 38464164
The COVID-19 pandemic persists despite the availability of vaccines, and it is therefore crucial to develop new therapeutic and preventive approaches. In this study, we investigated the potential role of...
4.
Guido T, Ratcliffe S, Rahmlow A, Zambrello M, Provates A, Clark R, et al.
Mol Oral Microbiol
. 2023 Oct;
39(3):103-112.
PMID: 37850509
Porphyromonas gingivalis produces five classes of serine/glycine lipids that are recovered in lipid extracts from periodontitis-afflicted teeth and diseased gingival tissues, particularly at sites of periodontitis. Because these lipids are...
5.
Pezzotti G, Adachi T, Imamura H, Bristol D, Adachi K, Yamamoto T, et al.
Int J Mol Sci
. 2023 Sep;
24(17).
PMID: 37686157
The aim of this study was to elucidate the chemistry of cellular degeneration in human neuroblastoma cells upon exposure to outer-membrane vesicles (OMVs) produced by () oral bacteria by monitoring...
6.
Yu B, Kanaan J, Shames H, Wicander J, Aryal M, Li Y, et al.
Front Microbiol
. 2023 Apr;
14:1161604.
PMID: 37113233
2Duf, named after the presence of a transmembrane (TM) Duf421 domain and a small Duf1657 domain in its sequence, is likely located in the inner membrane (IM) of spores in...
7.
Korza G, DePratti S, Fairchild D, Wicander J, Kanaan J, Shames H, et al.
J Appl Microbiol
. 2023 Feb;
134(3).
PMID: 36841229
Aims: This work aimed to characterize spore inner membrane (IM) properties and the mechanism of spore killing by wet heat and H2O2 with spores overexpressing the 2Duf protein, which is...
8.
Ludwig N, Demaree I, Yamada C, Nusbaum A, Nichols F, White F, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614317
Bacterial colonization of open wounds is common, and patients with infected wounds often report significantly elevated pain sensitivity at the wound site. Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels...
9.
Ranjit D, Moye Z, Rocha F, Ottenberg G, Nichols F, Kim H, et al.
Microbiol Spectr
. 2022 Mar;
10(2):e0000222.
PMID: 35286133
Like other members of the phylum , the oral anaerobe Porphyromonas gingivalis synthesizes a variety of sphingolipids, similar to its human host. Studies have shown that synthesis of these lipids...
10.
Millar C, Anto L, Garcia C, Kim M, Jain A, Provatas A, et al.
J Lipid Res
. 2022 Mar;
63(4):100192.
PMID: 35278409
Oral and gut Bacteroidetes produce unique classes of serine-glycine lipodipeptides and glycine aminolipids that signal through host Toll-like receptor 2. These glycine lipids have also been detected in human arteries,...