Francois Nedelec
Overview
Explore the profile of Francois Nedelec including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
2035
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Recent Articles
11.
Hannabuss J, Lera-Ramirez M, Cade N, Fourniol F, Nedelec F, Surrey T
Curr Biol
. 2019 Jun;
29(13):2120-2130.e7.
PMID: 31231047
In anaphase spindles, antiparallel microtubules associate to form tight midzone bundles, as required for functional spindle architecture and correct chromosome segregation. Several proteins selectively bind to these overlaps to control...
12.
Rickman J, Nedelec F, Surrey T
Phys Biol
. 2019 Apr;
16(4):046004.
PMID: 31013252
Active networks composed of filaments and motor proteins can self-organize into a variety of architectures. Computer simulations in two or three spatial dimensions and including or omitting steric interactions between...
13.
Letort G, Bennabi I, Dmitrieff S, Nedelec F, Verlhac M, Terret M
Mol Biol Cell
. 2019 Jan;
30(7):863-875.
PMID: 30650011
The mitotic spindle is an ensemble of microtubules responsible for the repartition of the chromosomal content between the two daughter cells during division. In metazoans, spindle assembly is a gradual...
14.
Wollrab V, Belmonte J, Baldauf L, Leptin M, Nedelec F, Koenderink G
J Cell Sci
. 2018 Nov;
132(4).
PMID: 30404824
Cytoskeletal networks of actin filaments and myosin motors drive many dynamic cell processes. A key characteristic of these networks is their contractility. Despite intense experimental and theoretical efforts, it is...
15.
Roostalu J, Rickman J, Thomas C, Nedelec F, Surrey T
Cell
. 2018 Oct;
175(3):796-808.e14.
PMID: 30340043
During cell division, mitotic motors organize microtubules in the bipolar spindle into either polar arrays at the spindle poles or a "nematic" network of aligned microtubules at the spindle center....
16.
Mund M, van der Beek J, Deschamps J, Dmitrieff S, Hoess P, Monster J, et al.
Cell
. 2018 Jul;
174(4):884-896.e17.
PMID: 30057119
Clathrin-mediated endocytosis is an essential cellular function in all eukaryotes that is driven by a self-assembled macromolecular machine of over 50 different proteins in tens to hundreds of copies. How...
17.
Burdyniuk M, Callegari A, Mori M, Nedelec F, Lenart P
J Cell Biol
. 2018 Jun;
217(8):2661-2674.
PMID: 29903878
Capture of each and every chromosome by spindle microtubules is essential to prevent chromosome loss and aneuploidy. In somatic cells, astral microtubules search and capture chromosomes forming lateral attachments to...
18.
Lacroix B, Letort G, Pitayu L, Salle J, Stefanutti M, Maton G, et al.
Dev Cell
. 2018 May;
45(4):496-511.e6.
PMID: 29787710
Successive cell divisions during embryonic cleavage create increasingly smaller cells, so intracellular structures must adapt accordingly. Mitotic spindle size correlates with cell size, but the mechanisms for this scaling remain...
19.
Descovich C, Cortes D, Ryan S, Nash J, Zhang L, Maddox P, et al.
Mol Biol Cell
. 2017 Dec;
29(5):622-631.
PMID: 29282285
Cell shape changes such as cytokinesis are driven by the actomyosin contractile cytoskeleton. The molecular rearrangements that bring about contractility in nonmuscle cells are currently debated. Specifically, both filament sliding...
20.
Gimpel P, Lee Y, Sobota R, Calvi A, Koullourou V, Patel R, et al.
Curr Biol
. 2017 Oct;
27(19):2999-3009.e9.
PMID: 28966089
The nucleus is the main microtubule-organizing center (MTOC) in muscle cells due to the accumulation of centrosomal proteins and microtubule (MT) nucleation activity at the nuclear envelope (NE) [1-4]. The...