Wei-Xiang Chew
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Explore the profile of Wei-Xiang Chew including associated specialties, affiliations and a list of published articles.
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5
Citations
16
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Recent Articles
1.
Lim W, Chew W, Esposito Verza A, Pesenti M, Musacchio A, Surrey T
Nat Commun
. 2024 Oct;
15(1):9213.
PMID: 39472429
During cell division, the microtubule cytoskeleton undergoes dramatic cell cycle-driven reorganizations of its architecture. Coordinated by changes in the phosphorylation patterns of a multitude of microtubule associated proteins, the mitotic...
2.
Scrofani J, Ruhnow F, Chew W, Normanno D, Nedelec F, Surrey T, et al.
Mol Biol Cell
. 2023 Nov;
35(1):ar12.
PMID: 37991893
Chromosome segregation relies on the correct assembly of a bipolar spindle. Spindle pole self-organization requires dynein-dependent microtubule (MT) transport along other MTs. However, during M-phase RanGTP triggers MT nucleation and...
3.
Chew W, Henkin G, Nedelec F, Surrey T
iScience
. 2023 Feb;
26(2):106063.
PMID: 36852161
Active filament networks can organize into various dynamic architectures driven by cross-linking motors. Densities and kinetic properties of motors and microtubules have been shown previously to determine active microtubule network...
4.
Henkin G, Chew W, Nedelec F, Surrey T
Proc Natl Acad Sci U S A
. 2022 Aug;
119(33):e2206398119.
PMID: 35960844
During cell division, cross-linking motors determine the architecture of the spindle, a dynamic microtubule network that segregates the chromosomes in eukaryotes. It is unclear how motors with opposite directionality coordinate...
5.
Chew W, Kaizu K, Watabe M, Muniandy S, Takahashi K, Arjunan S
Phys Rev E
. 2019 May;
99(4-1):042411.
PMID: 31108654
Microscopic models of reaction-diffusion processes on the cell membrane can link local spatiotemporal effects to macroscopic self-organized patterns often observed on the membrane. Simulation schemes based on the microscopic lattice...