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Francisco Duarte

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Articles 26
Citations 105
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Recent Articles
1.
Patel P, Bhattacharjee P, Gedi V, Duarte F, Tecza M, McGourty K, et al.
Int J Pharm . 2025 Jan; 671:125244. PMID: 39870254
The potent pro-inflammatory cytokine, interferon gamma (IFN-γ), is an enticing therapeutic target because of its accelerator role in several acute and chronic inflammatory processes. In this work, poloxamer 407 is...
2.
Bucarey S, Maldonado L, Duarte F, Hidalgo A, Saenz L
Vaccines (Basel) . 2025 Jan; 12(12. PMID: 39772060
Immunization against Gonadotropin-Releasing Hormone (GnRH) has been successfully explored and developed for the parenteral inoculation of animals, aimed at controlling fertility, reducing male aggressiveness, and preventing boar taint. Although effective,...
3.
Vellayappan M, Duarte F, Sollogoub C, Dirrenberger J, Guinault A, Frith J, et al.
Small . 2024 Jul; 20(43):e2401902. PMID: 38949308
The surface properties of biomaterials interact directly with biological systems, influencing cellular responses, tissue integration, and biocompatibility. Surface topography plays a critical role in cardiac tissue engineering by affecting electrical...
4.
Pita Ferreira P, Simoes D, Pinto de Carvalho C, Duarte F, Fernandes E, Carvalho P, et al.
JMIR AI . 2024 Jun; 2:e40965. PMID: 38875558
Background: In 2021, the European Union reported >270,000 excess deaths, including >16,000 in Portugal. The Portuguese Directorate-General of Health developed a deep neural network, AUTOCOD, which determines the primary causes...
5.
Duarte F, Tecza M, Gedi V, McGourty K, Hudson S
Cytokine . 2024 May; 180:156652. PMID: 38759527
C5a peptidase, also known as ScpA, is a surface associated serine protease derived from Streptococcus pyogenes and has been described as an important factor in streptococcus virulence, capable of cleaving...
6.
Brytan W, Shortall K, Duarte F, Soulimane T, Padrela L
Biochemistry . 2024 Apr; 63(9):1075-1088. PMID: 38602394
Aldehyde dehydrogenase enzymes (ALDHs) are widely studied for their roles in disease propagation and cell metabolism. Their use in biocatalysis applications, for the conversion of aldehydes to carboxylic acids, has...
7.
Preto A, Caniceiro A, Duarte F, Fernandes H, Ferreira L, Mourao J, et al.
J Cheminform . 2024 Feb; 16(1):18. PMID: 38365724
Cell-penetrating peptides (CPPs) are short chains of amino acids that have shown remarkable potential to cross the cell membrane and deliver coupled therapeutic cargoes into cells. Designing and testing different...
8.
Rocha R, Duarte F, Lima F, Mercado M, Araujo A, Garotti L, et al.
Int J Occup Saf Ergon . 2023 Dec; 30(1):224-237. PMID: 38083834
Approaches to safety culture assessment may have many limits if supported exclusively by quantitative methods. Based on this, a research team developed a quantitative-qualitative approach to assess the maturity of...
9.
Duarte F, Cordero E, Calderon M, Godinez A, Ross B, Allard M, et al.
Microbiol Resour Announc . 2023 Nov; 13(1):e0025723. PMID: 38019019
Here, we report the complete genome of four Infantis isolated in Costa Rica from human, poultry rinse, and raw chicken meat from 2017 to 2019. All genomes belonged to ST32...
10.
Gedi V, Duarte F, Patel P, Bhattacharjee P, Tecza M, McGourty K, et al.
Mol Pharm . 2023 Jul; 20(8):4041-4049. PMID: 37406301
Posttranslational modifications of proteins can impact their therapeutic efficacy, stability, and potential for pharmaceutical development. The Group AC5a peptidase (ScpA) is a multi-domain protein composed of an N-terminal signal peptide,...