Pratikkumar Patel
Overview
Explore the profile of Pratikkumar Patel including associated specialties, affiliations and a list of published articles.
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22
Citations
113
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Recent Articles
1.
Patel P, Bhattacharjee P, Gedi V, Duarte F, Tecza M, McGourty K, et al.
Int J Pharm
. 2025 Jan;
671:125244.
PMID: 39870254
The potent pro-inflammatory cytokine, interferon gamma (IFN-γ), is an enticing therapeutic target because of its accelerator role in several acute and chronic inflammatory processes. In this work, poloxamer 407 is...
2.
Zhao Z, Fetse J, Mamani U, Guo Y, Li Y, Patel P, et al.
Acta Biomater
. 2024 Dec;
193:484-497.
PMID: 39716541
Antibody-based checkpoint inhibitors have achieved great success in cancer immunotherapy, but their uncontrollable immune-related adverse events remain a major challenge. In this study, we developed a tumor-activated nanoparticle that is...
3.
Ahuja K, Muhammad U, Ahuja K, Haricharan R, Patel P
JPGN Rep
. 2024 Nov;
5(4):480-482.
PMID: 39610431
Kinetic magnetic sand, composed of ultra-fine sand and dimethicone in a 98%-2% ratio, is a versatile sensory toy known for its moldable properties and structural stability (1). Despite the name,...
4.
Shaji S, Patel P, Mamani U, Guo Y, Koirala S, Lin C, et al.
Int J Nanomedicine
. 2024 Sep;
19:8769-8778.
PMID: 39220196
Introduction: The tumor microenvironment (TME) of pancreatic cancer is highly immunosuppressive and characterized by a large number of cancer-associated fibroblasts, myeloid-derived suppressor cells, and regulatory T cells. Stimulator of interferon...
5.
Gedi V, Duarte F, Patel P, Bhattacharjee P, Tecza M, McGourty K, et al.
Mol Pharm
. 2023 Jul;
20(8):4041-4049.
PMID: 37406301
Posttranslational modifications of proteins can impact their therapeutic efficacy, stability, and potential for pharmaceutical development. The Group AC5a peptidase (ScpA) is a multi-domain protein composed of an N-terminal signal peptide,...
6.
Upadhyay C, DSouza A, Patel P, Verma V, Upadhayay K, Bharkatiya M
AAPS PharmSciTech
. 2023 Apr;
24(4):100.
PMID: 37029312
β-Cyclodextrin/ibuprofen inclusion complex was synthesized by freeze-drying method and characterized for phase solubility profiles, infrared spectra, thermal analysis, and X-ray powder diffractograms. The inclusion complex with HP-β-CD, as confirmed by...
7.
Ryan A, Patel P, Ratrey P, OConnor P, OSullivan J, Ross R, et al.
Drug Deliv Transl Res
. 2023 Mar;
13(9):2407-2423.
PMID: 36964439
Chronic wounds affect millions of people globally. This number is set to rise with the increasing incidence of antimicrobial-resistant bacterial infections, such as methicillin-resistant Staphylococcus aureus (MRSA), which impair the...
8.
Patel P, Fetse J, Lin C, Guo Y, Hasan M, Nakhjiri M, et al.
Acta Biomater
. 2022 Oct;
154:374-384.
PMID: 36191773
The use of siRNA therapeutics to treat cancer is a very promising approach. However, specific delivery of siRNAs to tumors remains a major challenge. The recent success of siRNA delivery...
9.
Fetse J, Zhao Z, Liu H, Mamani U, Mustafa B, Adhikary P, et al.
J Med Chem
. 2022 Sep;
65(18):12002-12013.
PMID: 36067356
Blockade of the interaction between programmed cell death ligand-1 (PD-L1) and its receptor PD-1 has shown great success in cancer immunotherapy. Peptides possess unique characteristics that give them significant advantages...
10.
Ryan A, Patel P, OConnor P, Cookman J, Ross R, Hill C, et al.
Eur J Pharm Biopharm
. 2022 May;
176:199-210.
PMID: 35640784
The bacteriocin lacticin 3147 (lacticin) has shown activity against clinically relevant and antimicrobial-resistant bacteria such as Listeria monocytogenes and Clostridioides difficile. It is composed of two peptides, Ltnα and Ltnβ,...