Francesco Giansanti
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Explore the profile of Francesco Giansanti including associated specialties, affiliations and a list of published articles.
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37
Citations
488
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Recent Articles
11.
Ponziani S, Di Vittorio G, Pitari G, Cimini A, Ardini M, Gentile R, et al.
Int J Mol Sci
. 2020 Aug;
21(15).
PMID: 32752132
In recent years, antibody-drug conjugates (ADCs) have become promising antitumor agents to be used as one of the tools in personalized cancer medicine. ADCs are comprised of a drug with...
12.
Ardini M, Huang J, Caprettini V, De Angelis F, Fata F, Silvestri I, et al.
Biochim Biophys Acta Gen Subj
. 2020 Apr;
1864(8):129617.
PMID: 32304715
Background: Proteins are efficient supramolecular scaffolds to drive self-assembly of nanomaterials into regular colloidal structures suitable for several purposes, including cell imaging and drug delivery. Proteins, in particular, can bind...
13.
Giansanti F, Capone E, Ponziani S, Piccolo E, Gentile R, Lamolinara A, et al.
J Control Release
. 2018 Dec;
294:176-184.
PMID: 30553852
Galectin-3-binding protein (Gal-3BP) has been identified as a cancer and metastasis-associated, secreted protein that is expressed by the large majority of cancers. The present study describes a special type of...
14.
Cimini A, Ardini M, Gentile R, Giansanti F, Benedetti E, Cristiano L, et al.
J Tissue Eng Regen Med
. 2018 May;
11(9):2462-2470.
PMID: 29737636
The use of nanoscale materials in the design of scaffolds for CNS tissue is increasing, due to their ability to promote cell adhesion, to mimic an extracellular matrix microenvironment and...
15.
Giansanti F, Flavell D, Angelucci F, Fabbrini M, Ippoliti R
Toxins (Basel)
. 2018 Feb;
10(2).
PMID: 29438358
Plant Ribosome-inactivating proteins (RIPs) including the type I RIP Saporin have been used for the construction of Immunotoxins (ITxs) obtained via chemical conjugation of the toxic domain to whole antibodies...
16.
Solis More Y, Panella G, Fioravanti G, Perrozzi F, Passacantando M, Giansanti F, et al.
J Biomed Mater Res A
. 2018 Feb;
106(6):1585-1594.
PMID: 29424473
Novel two-dimensional films and three-dimensional (3D) scaffolds based on chitosan (CHI), apatite (Ap), and graphene oxide (GO) were developed by an in situ synthesis in which self-assembly process was conducted...
17.
Capone E, Giansanti F, Ponziani S, Lamolinara A, Iezzi M, Cimini A, et al.
Oncotarget
. 2017 Dec;
8(56):95412-95424.
PMID: 29221137
Melanoma is the most biologically aggressive skin cancer of well established constitutive and induced resistance to pharmacological treatment. Despite the recent progresses in immunotherapies, many advanced metastatic melanoma patients still...
18.
Dhez A, Benedetti E, Antonosante A, Panella G, Ranieri B, Florio T, et al.
J Cell Physiol
. 2017 Sep;
233(5):4091-4105.
PMID: 28941284
Targeted anticancer therapies demand discovery of new cellular targets to be exploited for the delivery of toxic molecules and drugs. In this perspective, in the last few years, nucleolin has...
19.
Errico Provenzano A, Posteri R, Giansanti F, Angelucci F, Flavell S, Flavell D, et al.
Microb Cell Fact
. 2016 Nov;
15(1):194.
PMID: 27842546
Background: The big challenge in any anti-tumor therapeutic approach is represented by the development of drugs selectively acting on the target with limited side effects, that exploit the unique characteristics...
20.
Giansanti F, Panella G, Leboffe L, Antonini G
Pharmaceuticals (Basel)
. 2016 Oct;
9(4).
PMID: 27690059
Lactoferrin is an iron-binding protein present in large quantities in colostrum and in breast milk, in external secretions and in polymorphonuclear leukocytes. Lactoferrin's main function is non-immune protection. Among several...