Francesco Frecentese
Overview
Explore the profile of Francesco Frecentese including associated specialties, affiliations and a list of published articles.
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Articles
67
Citations
317
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Recent Articles
1.
Schiano M, Billi C, Grillo G, Tkachuk O, De Caro C, Russo E, et al.
ChemMedChem
. 2024 Nov;
20(5):e202400721.
PMID: 39561040
7-methyl-2-phenylimidazo[1,2-b]pyridazin-3-carboxylic acid (DM1) and 6-methoxy-2-phenylimidazo[1,2-b]pyridazin-3-carboxylic acid (DM2) have been shown to act as human (h) Cav voltage-gated calcium channel blockers with promising in vivo anti-absence activity, positioning them as potential...
2.
Andreozzi G, Corvino A, Severino B, Magli E, Perissutti E, Frecentese F, et al.
Pharmaceuticals (Basel)
. 2024 Oct;
17(10).
PMID: 39458961
In recent decades, there has been a startling rise in the number of cancer patients worldwide, which has led to an amazing upsurge in the development of novel anticancer treatment...
3.
Oliveira D, Cardoso V, Britto-Junior J, Fuguhara V, Frecentese F, Sparaco R, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2024 Oct;
PMID: 39382679
The positive chronotropic action induced by 6-nitrodopamine (6-ND) is selectively blocked by β-adrenoceptor antagonists at concentrations that do not affect the positive chronotropic effect induced by dopamine, noradrenaline, and adrenaline....
4.
Miranda D, Cerqueira A, Muscara M, Severino B, Caliendo G, Corvino A, et al.
Eur J Pharm Sci
. 2024 Oct;
203:106925.
PMID: 39374744
Psoriasis is an immune-mediated chronic inflammatory disease that causes major psychosocial impact. Topical corticosteroids represent the standard pharmacological treatment for mild-to-moderate disease, but their local and systemic adverse effects reinforce...
5.
Corvino A, Granato E, Scognamiglio A, Fiorino F, Frecentese F, Magli E, et al.
Molecules
. 2024 Sep;
29(18).
PMID: 39339509
In this study, a new and straightforward process for the preparation of budesonide 21-phosphate (Bud-21P) and its disodium salt (Bud-21P-Na2) is described. The method results in a yield comparable to...
6.
Corvino A, Caliendo G, Fiorino F, Frecentese F, Valsecchi V, Lombardi G, et al.
ACS Pharmacol Transl Sci
. 2024 Jul;
7(7):1996-2005.
PMID: 39022351
The debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motor neurons (MNs) in the brain, spinal cord, and motor cortex. The ALS...
7.
Scognamiglio A, Cerqua I, Citi V, Martelli A, Spezzini J, Calderone V, et al.
Eur J Med Chem
. 2024 Jun;
275:116636.
PMID: 38944936
Asthma is a major noncommunicable disease, affecting both children and adults, and represents one of the major causes leading to high health care costs due to the need for chronic...
8.
Villapiano F, Di Lorenzo R, Sparaco R, Magli E, Frecentese F, Laneri S, et al.
Biomedicines
. 2024 Apr;
12(4).
PMID: 38672133
Chronic wounds are marked by an extended healing period during which damaged tissues fail to undergo orderly and timely repair. Examples of chronic wounds encompass venous ulcers, pressure ulcers, and...
9.
Britto-Junior J, Furlaneto R, Lima A, de Oliveira M, Severino B, Frecentese F, et al.
Front Pharmacol
. 2024 Apr;
15:1348876.
PMID: 38645555
The human umbilical artery (HUA), rat-isolated right atrium, and rat-isolated vas deferens present a basal release of 6-nitrodopamine (6-ND). The basal release of 6-ND from these tissues was significantly decreased...
10.
Sparaco R, Cinque P, Scognamiglio A, Corvino A, Caliendo G, Fiorino F, et al.
Molecules
. 2024 Apr;
29(7).
PMID: 38611877
4-Nitro and 7-nitro propranolol have been recently synthesized and characterized by us. (±)-4-NO-propranolol has been shown to act as a selective antagonist of 6-nitrodopamine (6-ND) receptors in the right atrium...