Beatrice Severino
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Explore the profile of Beatrice Severino including associated specialties, affiliations and a list of published articles.
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84
Citations
507
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Recent Articles
1.
Andreozzi G, Corvino A, Severino B, Magli E, Perissutti E, Frecentese F, et al.
Pharmaceuticals (Basel)
. 2024 Oct;
17(10).
PMID: 39458961
In recent decades, there has been a startling rise in the number of cancer patients worldwide, which has led to an amazing upsurge in the development of novel anticancer treatment...
2.
Miranda D, Cerqueira A, Muscara M, Severino B, Caliendo G, Corvino A, et al.
Eur J Pharm Sci
. 2024 Oct;
203:106925.
PMID: 39374744
Psoriasis is an immune-mediated chronic inflammatory disease that causes major psychosocial impact. Topical corticosteroids represent the standard pharmacological treatment for mild-to-moderate disease, but their local and systemic adverse effects reinforce...
3.
Corvino A, Granato E, Scognamiglio A, Fiorino F, Frecentese F, Magli E, et al.
Molecules
. 2024 Sep;
29(18).
PMID: 39339509
In this study, a new and straightforward process for the preparation of budesonide 21-phosphate (Bud-21P) and its disodium salt (Bud-21P-Na2) is described. The method results in a yield comparable to...
4.
Corvino A, Caliendo G, Fiorino F, Frecentese F, Valsecchi V, Lombardi G, et al.
ACS Pharmacol Transl Sci
. 2024 Jul;
7(7):1996-2005.
PMID: 39022351
The debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motor neurons (MNs) in the brain, spinal cord, and motor cortex. The ALS...
5.
Corvino A, Scognamiglio A, Fiorino F, Perissutti E, Santagada V, Caliendo G, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000122
Among the various drug discovery methods, a very promising modern approach consists in designing multi-target-directed ligands (MTDLs) able to modulate multiple targets of interest, including the pathways where hydrogen sulfide...
6.
Scognamiglio A, Cerqua I, Citi V, Martelli A, Spezzini J, Calderone V, et al.
Eur J Med Chem
. 2024 Jun;
275:116636.
PMID: 38944936
Asthma is a major noncommunicable disease, affecting both children and adults, and represents one of the major causes leading to high health care costs due to the need for chronic...
7.
Britto-Junior J, Furlaneto R, Lima A, de Oliveira M, Severino B, Frecentese F, et al.
Front Pharmacol
. 2024 Apr;
15:1348876.
PMID: 38645555
The human umbilical artery (HUA), rat-isolated right atrium, and rat-isolated vas deferens present a basal release of 6-nitrodopamine (6-ND). The basal release of 6-ND from these tissues was significantly decreased...
8.
Sparaco R, Cinque P, Scognamiglio A, Corvino A, Caliendo G, Fiorino F, et al.
Molecules
. 2024 Apr;
29(7).
PMID: 38611877
4-Nitro and 7-nitro propranolol have been recently synthesized and characterized by us. (±)-4-NO-propranolol has been shown to act as a selective antagonist of 6-nitrodopamine (6-ND) receptors in the right atrium...
9.
Cerqua I, Granato E, Corvino A, Severino B, DAvino D, Simonelli M, et al.
Front Pharmacol
. 2023 Oct;
14:1266934.
PMID: 37900172
Hydrogen sulfide (HS) is emerging as an important potential therapeutic option for respiratory inflammatory diseases. In this study, we investigated the effectiveness of a novel corticosteroid derivative, that is chemically...
10.
Andreozzi G, Ambrosio M, Magli E, Maneli G, Severino B, Corvino A, et al.
Pharmaceuticals (Basel)
. 2023 Oct;
16(10).
PMID: 37895954
Arylpiperazines represent one of the most important classes of 5-HTR ligands and have attracted considerable interests for their versatile properties in chemistry and pharmacology, leading to the research of new...