Francesca Sassone
Overview
Explore the profile of Francesca Sassone including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
156
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0
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Recent Articles
1.
Pommereau A, Sassone F, Poli A, De Silvestris M, Scarabottolo L, Zuschlag Y, et al.
SLAS Discov
. 2024 Nov;
29(8):100193.
PMID: 39522878
GLUT9/SLC2A9 is a urate transporter and takes a fundamental role in the maintenance of normal serum urate levels. GLUT9 is the sole transporter of reabsorbed urate from renal epithelial cells...
2.
Digles D, Ingles-Prieto A, Dvorak V, Mocking T, Goldmann U, Garofoli A, et al.
Front Pharmacol
. 2024 Jul;
15:1401599.
PMID: 39050757
With over 450 genes, solute carriers (SLCs) constitute the largest transporter superfamily responsible for the uptake and efflux of nutrients, metabolites, and xenobiotics in human cells. SLCs are associated with...
3.
Dvorak V, Wiedmer T, Ingles-Prieto A, Altermatt P, Batoulis H, Barenz F, et al.
Front Pharmacol
. 2021 Aug;
12:722889.
PMID: 34447313
The solute carrier (SLC) superfamily represents the biggest family of transporters with important roles in health and disease. Despite being attractive and druggable targets, the majority of SLCs remains understudied....
4.
Superti-Furga G, Lackner D, Wiedmer T, Ingles-Prieto A, Barbosa B, Girardi E, et al.
Nat Rev Drug Discov
. 2020 Apr;
19(7):429-430.
PMID: 32265506
No abstract available.
5.
Bardelli D, Sassone F, Colombrita C, Volpe C, Gumina V, Peverelli S, et al.
J Cell Mol Med
. 2020 Mar;
24(7):4051-4060.
PMID: 32125773
As for the majority of neurodegenerative diseases, pathological mechanisms of amyotrophic lateral sclerosis (ALS) have been challenging to study due to the difficult access to alive patients' cells. Induced pluripotent...
6.
Bossolasco P, Sassone F, Gumina V, Peverelli S, Garzo M, Silani V
Stem Cell Res
. 2018 May;
30:61-68.
PMID: 29800782
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease, mainly affecting the motor neurons (MNs) and without effective therapy. Drug screening is hampered by the lack of satisfactory experimental and...
7.
Sassone F, Margulets V, Maraschi A, Rodighiero S, Passafaro M, Silani V, et al.
Hum Mol Genet
. 2015 Sep;
24(22):6530-9.
PMID: 26358776
Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of a CAG repeat in the IT15 gene that encodes the protein huntingtin (htt). Evidence shows that mutant htt...
8.
Solca F, Poletti B, Zago S, Crespi C, Sassone F, Lafronza A, et al.
PLoS One
. 2015 Jun;
10(6):e0126773.
PMID: 26070155
Background And Objective: Counterfactual thinking (CFT) refers to the generation of mental simulations of alternatives to past events, actions and outcomes. CFT is a pervasive cognitive feature in every-day life...
9.
Maraschi A, Ciammola A, Folci A, Sassone F, Ronzitti G, Cappelletti G, et al.
Nat Commun
. 2014 Oct;
5:5182.
PMID: 25316086
Although loss-of-function mutations in the PARK2 gene, the gene that encodes the protein parkin, cause autosomal recessive juvenile parkinsonism, the responsible molecular mechanisms remain unclear. Evidence suggests that a loss...
10.
Bazzini C, Rossetti V, Civello D, Sassone F, Vezzoli V, Persani L, et al.
Cell Physiol Biochem
. 2014 Jan;
32(7):129-45.
PMID: 24429820
Background: Cigarette smoke extract (CSE), a model for studying the effects of tobacco smoke in vivo and in vitro, induces cell oxidative stress and affects the antioxidative glutathione system. We...