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Francesca Hofer

Explore the profile of Francesca Hofer including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 337
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Recent Articles
1.
Hofer F, Di Sario G, Musiu C, Sartoris S, De Sanctis F, Ugel S
Cells . 2021 Oct; 10(10). PMID: 34685679
Myeloid-derived suppressor cells (MDSCs) constitute a plastic and heterogeneous cell population among immune cells within the tumour microenvironment (TME) that support cancer progression and resistance to therapy. During tumour progression,...
2.
Musiu C, Caligola S, Fiore A, Lamolinara A, Frusteri C, Del Pizzo F, et al.
Cell Death Differ . 2021 Sep; 29(2):420-438. PMID: 34518653
Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively known as cytokine release syndrome (CRS), exemplified by...
3.
Bronte V, Ugel S, Tinazzi E, Vella A, De Sanctis F, Cane S, et al.
J Clin Invest . 2020 Aug; 130(12):6409-6416. PMID: 32809969
BACKGROUNDPatients with coronavirus disease 2019 (COVID-19) develop pneumonia generally associated with lymphopenia and a severe inflammatory response due to uncontrolled cytokine release. These mediators are transcriptionally regulated by the JAK/STAT...
4.
Marigo I, Trovato R, Hofer F, Ingangi V, Desantis G, Leone K, et al.
Cancer Discov . 2020 Jul; 10(11):1758-1773. PMID: 32651166
Tumor-associated macrophages (TAM) are regulators of extracellular matrix (ECM) remodeling and metastatic progression, the main cause of cancer-associated death. We found that disabled homolog 2 mitogen-responsive phosphoprotein (DAB2) is highly...
5.
Trovato R, Fiore A, Sartori S, Cane S, Giugno R, Cascione L, et al.
J Immunother Cancer . 2019 Sep; 7(1):255. PMID: 31533831
Background: Pancreatic ductal adenocarcinoma (PDAC) is a highly devastating disease with an overall 5-year survival rate of less than 8%. New evidence indicates that PDAC cells release pro-inflammatory metabolites that...