Francesca Esposito
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Explore the profile of Francesca Esposito including associated specialties, affiliations and a list of published articles.
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Articles
143
Citations
1527
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Recent Articles
1.
Zian D, Iaconis D, Nenci S, Crusco A, Tawde S, Sodano M, et al.
Antiviral Res
. 2025 Feb;
237:106119.
PMID: 39978553
The COVID-19 pandemic highlighted the importance of accelerating the drug discovery process. The 3-chymotrypsin-like protease (3CLpro) is a critical enzyme in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral...
2.
Esposito F, de Lellis F, De Cordova F, Briozzo E
Am J Community Psychol
. 2025 Feb;
PMID: 39943892
In this paper, we examine immigration detention in Portugal, a system whose daily operations and inherent violence are overlooked in both public and academic discourses. Even within community psychology, discussions...
3.
Kuzikov M, Morasso S, Reinshagen J, Wolf M, Monaco V, Cozzolino F, et al.
ACS Pharmacol Transl Sci
. 2025 Jan;
8(1):66-77.
PMID: 39816795
The SARS-CoV-2 papain-like protease PLpro has multiple roles in the viral replication cycle, related to both its polypeptide cleavage function and its ability to antagonize the host immune response. Targeting...
4.
Iacobucci I, Cipollone I, Cozzolino F, Iaconis D, Talarico C, Coppola G, et al.
Int J Biol Macromol
. 2025 Jan;
295:139590.
PMID: 39788258
SARS-CoV-2 encodes a 3C-like protease (3CL) that is essential for viral replication. This cysteine protease cleaves viral polyproteins to release functional nonstructural proteins, making it a prime target for antiviral...
5.
Baroni S, Carletti T, Donalisio M, Arduino I, Cazzaniga I, Giorgino T, et al.
Front Cell Infect Microbiol
. 2024 Dec;
14:1487604.
PMID: 39654978
Coronaviruses (CoVs) share key genomic elements critical for viral replication, suggesting the feasibility of developing therapeutics with efficacy across different viruses. In a previous work, we demonstrated the antiviral activity...
6.
Modafferi S, Esposito F, Tavella S, Gioia U, Francia S
FEBS Lett
. 2024 Sep;
599(2):177-189.
PMID: 39333024
Transcription of actively expressed genes is dampened for kilobases around DNA lesions via chromatin modifications. This is believed to favour repair and prevent genome instability. Nonetheless, mounting evidence suggests that...
7.
Puxeddu M, Donalisio M, Bugert J, Corona A, Cocomazzi P, Milani M, et al.
ACS Infect Dis
. 2024 Aug;
10(9):3158-3175.
PMID: 39096289
SARS-CoV-2 and HCoV-OC43 belong to the same β genus of the Coronaviridae family. SARS-CoV-2 was responsible for the recent COVID-19 pandemic, and HCoV-OC43 is the etiological agent of mild upper...
8.
Messore A, Malune P, Patacchini E, Madia V, Ialongo D, Arpacioglu M, et al.
Pharmaceuticals (Basel)
. 2024 May;
17(5).
PMID: 38794220
It has been more than four years since the first report of SARS-CoV-2, and humankind has experienced a pandemic with an unprecedented impact. Moreover, the new variants have made the...
9.
Esposito F, Nappi F, Urraro F, Vitillo P, Rotondi F
Eur Heart J Case Rep
. 2024 May;
8(5):ytae201.
PMID: 38711682
Background: The Brugada syndrome (BrS) is an inherited disorder associated with the risk of ventricular fibrillation and sudden cardiac death (SCD). The current main therapy is an implantable cardioverter-defibrillator (ICD)....
10.
Kuzikov M, Reinshagen J, Wycisk K, Corona A, Esposito F, Malune P, et al.
Virus Res
. 2024 Mar;
343:199356.
PMID: 38490582
Coronaviruses contain one of the largest genomes among the RNA viruses, coding for 14-16 non-structural proteins (nsp) that are involved in proteolytic processing, genome replication and transcription, and four structural...