Francesca Anson
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Explore the profile of Francesca Anson including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
74
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Recent Articles
1.
Miranda R, Anson F, Smith S, Ultsch M, Tenorio C, Rouge L, et al.
Structure
. 2025 Feb;
PMID: 39983720
The ubiquitin-specific protease (USP) family of deubiquitinases (DUBs) are regulators of Ub signaling that share a common catalytic-domain fold. The dynamic nature of this domain is important for controlling the...
2.
Exogenous Introduction of Initiator and Executioner Caspases Results in Different Apoptotic Outcomes
Anson F, Thayumanavan S, Hardy J
JACS Au
. 2021 Sep;
1(8):1240-1256.
PMID: 34467362
The balance of pro-apoptotic and pro-survival proteins defines a cell's fate. These processes are controlled through an interdependent and finely tuned protein network that enables survival or leads to apoptotic...
3.
Anson F, Liu B, Kanjilal P, Wu P, Hardy J, Thayumanavan S
Biomacromolecules
. 2021 Feb;
22(3):1261-1272.
PMID: 33591168
The ability for biologics to access intracellular targets hinges on the translocation of active, unmodified proteins. This is often achieved using nanoscale formulations, which enter cells through endocytosis. This uptake...
4.
Anson F, Kanjilal P, Thayumanavan S, Hardy J
Protein Sci
. 2020 Nov;
30(2):366-380.
PMID: 33165988
Cytosolic protein delivery promises diverse applications from therapeutics, to genetic modification and precision research tools. To achieve effective cellular and subcellular delivery, approaches that allow protein visualization and accurate localization...
5.
Koyasseril-Yehiya T, Garcia-Heredia A, Anson F, Rangadurai P, Siegrist M, Thayumanavan S
Nanoscale
. 2020 Oct;
12(40):20693-20698.
PMID: 33029599
The propensity of broad-spectrum antibiotics to indiscriminately kill both pathogenic and beneficial bacteria has a profound impact on the spread of resistance across multiple bacterial species. Alternative approaches that narrow...
6.
Liu B, Ejaz W, Gong S, Kurbanov M, Canakci M, Anson F, et al.
Nano Lett
. 2020 Apr;
20(5):4014-4021.
PMID: 32298126
Intracellular delivery of functional proteins is a promising, but challenging, strategy for many therapeutic applications. Here, we report a new methodology that overcomes drawbacks of traditional mesoporous silica (MSi) particles...
7.
Zentner C, Anson F, Thayumanavan S, Swager T
J Am Chem Soc
. 2019 Nov;
141(45):18048-18055.
PMID: 31674769
Interfacial chemistry provides an opportunity to control dynamic materials. By harnessing the dynamic covalent nature of imine bonds, emulsions are generated in situ, predictably manipulated, and ultimately destroyed along liquid-liquid...
8.
Gordon M, Zhao B, Anson F, Fernandez A, Singh K, Homyak C, et al.
Biomacromolecules
. 2018 Jan;
19(3):860-871.
PMID: 29360342
Here, we have exploited the heightened extracellular concentration of matrix metalloproteinase-9 (MMP-9) to induce surface-conversional properties of nanogels with the aim of tumor-specific enhanced cellular uptake. A modular polymeric nanogel...
9.
Homyak C, Fernandez A, Touve M, Zhao B, Anson F, Hardy J, et al.
Biomacromolecules
. 2017 Nov;
19(1):132-140.
PMID: 29141403
Lipid-polymer hybrid materials have the potential to exhibit enhanced stability and loading capabilities in comparison to parent liposome or polymer materials. However, complexities lie in formulating and characterizing such complex...
10.
Raghupathi K, Eron S, Anson F, Hardy J, Thayumanavan S
Mol Pharm
. 2017 Oct;
14(12):4515-4524.
PMID: 29053277
Therapeutic biologics have various advantages over synthetic drugs in terms of selectivity, their catalytic nature, and, thus, therapeutic efficacy. These properties offer the potential for more effective treatments that may...