Frances Neal
Overview
Explore the profile of Frances Neal including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
163
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0
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Recent Articles
1.
Chin S, Gallego P, Aagaard A, Carmen S, Barrett N, Wolny M, et al.
SLAS Discov
. 2025 Jan;
31:100216.
PMID: 39832740
Neurotrophic factor 3 (NTF3) is a cysteine knot protein and a member of the nerve growth factor (NGF) family of cytokines. NTF3 engages the Trk family of receptor tyrosine kinases,...
2.
Dovedi S, Elder M, Yang C, Sitnikova S, Irving L, Hansen A, et al.
Cancer Discov
. 2021 Jan;
11(5):1100-1117.
PMID: 33419761
The clinical benefit of PD-1 blockade can be improved by combination with CTLA4 inhibition but is commensurate with significant immune-related adverse events suboptimally limiting the doses of anti-CTLA4 mAb that...
3.
Zhou Y, Chen B, Mittereder N, Chaerkady R, Strain M, An L, et al.
Front Immunol
. 2017 Oct;
8:1200.
PMID: 28993780
Autoantibodies directed against citrullinated epitopes of proteins are highly diagnostic of rheumatoid arthritis (RA), and elevated levels of protein citrullination can be found in the joints of patients with RA....
4.
Neal F, Arnold J, Rossant C, Podichetty S, Lowne D, Dobson C, et al.
J Biomol Screen
. 2015 Oct;
21(1):24-34.
PMID: 26450103
Calcitonin gene-related peptide (CGRP) is a small neuropeptide and a potent vasodilator that is widely associated with chronic pain and migraine. An antibody that inhibits CGRP function would be a...
5.
Rossant C, Carroll D, Huang L, Elvin J, Neal F, Walker E, et al.
MAbs
. 2014 Dec;
6(6):1425-38.
PMID: 25484064
Generation of functional antibodies against integral membrane proteins such as the G-protein coupled receptor CXCR2 is technically challenging for several reasons, including limited epitope accessibility, the requirement for a lipid...
6.
England E, Newton P, Neal F, Kitching L, Colley C, Rossant C
J Biomol Screen
. 2014 Nov;
20(4):536-44.
PMID: 25381256
Highly sensitive, high-throughput assay technologies are required for the identification of antibody therapeutics. Multiplexed assay systems are particularly advantageous because they allow evaluation of several parameters within 1 well, increasing...
7.
Rossant C, Matthews C, Neal F, Colley C, Gardener M, Vaughan T
J Biomol Screen
. 2014 Nov;
20(4):508-18.
PMID: 25381254
Identification of potential lead antibodies in the drug discovery process requires the use of assays that not only measure binding of the antibody to the target molecule but assess a...