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Fouad Lafdil

Explore the profile of Fouad Lafdil including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1666
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Recent Articles
1.
Ait-Ahmed Y, Lafdil F
Liver Res . 2025 Feb; 7(1):26-34. PMID: 39959704
Primary liver cancers rank among the deadliest cancers worldwide and often develop in patients with chronic liver diseases in an inflammatory context. This review highlights recent reports on the mechanisms...
2.
Brouillet A, Lafdil F
eGastroenterology . 2025 Feb; 1(1):e100010. PMID: 39944247
Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third-leading cause of cancer-related death in 2020. Despite encouraging findings on diagnosis and treatments, liver cancer remains...
3.
Hao Y, Song S, Li T, Zai Q, Ma N, Li Y, et al.
Int J Biol Sci . 2024 May; 20(7):2422-2439. PMID: 38725842
: Reactive oxygen species (ROS) act as modulators triggering cellular dysfunctions and organ damage including liver fibrosis in which hepatic stellate cell (HSC) activation plays a key role. Previous studies...
4.
Ait Ahmed Y, Lafdil F, Tacke F
Hepat Med . 2023 Sep; 15:113-127. PMID: 37753346
Alcohol-associated liver disease (ALD) represents a major public health issue worldwide and is a leading etiology of liver cirrhosis. Alcohol-related liver injuries include a range of manifestations including alcoholic hepatitis...
5.
Gasmi I, Machou C, Rodrigues A, Brouillet A, Nguyen T, Rousseau B, et al.
Int J Biol Sci . 2022 Mar; 18(5):1944-1960. PMID: 35342340
Chronic inflammation is a key component in the development of virtually all types of primary liver cancers. However, how chronic inflammation potentiates or even may initiate liver parenchymal cell transformation...
6.
Nguyen C, Caruso S, Maille P, Beaufrere A, Augustin J, Favre L, et al.
Clin Cancer Res . 2021 Nov; 28(3):540-551. PMID: 34785581
Purpose: Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare malignancy associated with an overall poor prognosis. We aimed to investigate the immune profile of cHCC-CCA and determine its impact on disease outcome....
7.
Benoit C, Rodrigues A, Calderaro J, Charpy C, Simonin S, Deybach J, et al.
Eur Radiol . 2021 Oct; 32(4):2481-2491. PMID: 34694452
Objectives: To assess the performance of 405 nm-induced autofluorescence for the characterization of primary liver nodules on ex vivo resected specimens. Materials And Methods: Forty resected liver specimens bearing 53...
8.
Ait Ahmed Y, Fu Y, Rodrigues R, He Y, Guan Y, Guillot A, et al.
Cell Mol Immunol . 2021 Jul; 18(9):2165-2176. PMID: 34282300
Kupffer cells (KCs), which are liver-resident macrophages, originate from the fetal yolk sac and represent one of the largest macrophage populations in the body. However, the current data on the...
9.
He Y, Hwang S, Ait Ahmed Y, Feng D, Li N, Ribeiro M, et al.
Cell Mol Immunol . 2020 Nov; 18(1):18-37. PMID: 33203939
Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a variety of factors,...
10.
Meylan M, Petitprez F, Lacroix L, Di Tommaso L, Roncalli M, Bougouin A, et al.
Clin Cancer Res . 2020 Apr; 26(16):4381-4389. PMID: 32269054
Purpose: The impact of tertiary lymphoid structures (TLS) in hepatocellular carcinoma (HCC) progression is being extensively investigated. However, their presence during the early steps of human liver carcinogenesis remains unknown....