Florian J Bock
Overview
Explore the profile of Florian J Bock including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
1255
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bock F, Sedov E, Koren E, Koessinger A, Cloix C, Zerbst D, et al.
Nat Commun
. 2024 Feb;
15(1):1815.
PMID: 38418481
No abstract available.
2.
Bock F, Riley J
Cell Death Differ
. 2022 Nov;
30(2):293-303.
PMID: 36376381
Apoptosis is a regulated cellular pathway that ensures that a cell dies in a structured fashion to prevent negative consequences for the tissue or the organism. Dysfunctional apoptosis is a...
3.
Riley J, Bock F
Biochim Biophys Acta Mol Cell Res
. 2022 Aug;
1869(11):119341.
PMID: 35987283
Programmed cell death, in particular apoptosis, has vital functions in every healthy organism. In a highly regulated manner cells which are no longer needed or are harmful to the organism...
4.
Koessinger A, Cloix C, Koessinger D, Heiland D, Bock F, Strathdee K, et al.
Cell Death Differ
. 2022 Apr;
29(10):2089-2104.
PMID: 35473984
Glioblastoma (GBM) is the most prevalent malignant primary brain tumour in adults. GBM typically has a poor prognosis, mainly due to a lack of effective treatment options leading to tumour...
5.
Bock F, Sedov E, Koren E, Koessinger A, Cloix C, Zerbst D, et al.
Nat Commun
. 2021 Nov;
12(1):6572.
PMID: 34772930
Damaged or superfluous cells are typically eliminated by apoptosis. Although apoptosis is a cell-autonomous process, apoptotic cells communicate with their environment in different ways. Here we describe a mechanism whereby...
6.
Bock F, Tait S
Nat Rev Mol Cell Biol
. 2019 Oct;
21(2):85-100.
PMID: 31636403
Through their many and varied metabolic functions, mitochondria power life. Paradoxically, mitochondria also have a central role in apoptotic cell death. Upon induction of mitochondrial apoptosis, mitochondrial outer membrane permeabilization...
7.
Chauhan D, Bartok E, Gaidt M, Bock F, Herrmann J, Seeger J, et al.
Cell Rep
. 2018 Nov;
25(9):2354-2368.e5.
PMID: 30485805
IL-1β is a cytokine of pivotal importance to the orchestration of inflammatory responses. Synthesized as an inactive pro-cytokine, IL-1β requires proteolytic maturation to gain biological activity. Here, we identify intrinsic...
8.
Bock F, Chang P
Methods Mol Biol
. 2018 Aug;
1813:327-341.
PMID: 30097879
Posttranscriptional regulation of RNA is an important component of gene expression by controlling the total amount of mRNA available for translation into protein. It involves multiple pathways including nuclear processing...
9.
10.
Pecot J, Maillet L, Le Pen J, Vuillier C, de Carne Trecesson S, Fetiveau A, et al.
Cell Rep
. 2016 Dec;
17(12):3347-3358.
PMID: 28009301
Anti-apoptotic BCL-2 family members bind to BH3-only proteins and multidomain BAX/BAK to preserve mitochondrial integrity and maintain survival. Whereas inhibition of these interactions is the biological basis of BH3-mimetic anti-cancer...