Flora I Hinz
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Explore the profile of Flora I Hinz including associated specialties, affiliations and a list of published articles.
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11
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549
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Recent Articles
1.
Hinz F, Villegas C, Roberts J, Yao H, Gaddam S, Delwig A, et al.
J Neurosci
. 2024 May;
44(24).
PMID: 38692735
Sterile alpha and TIR motif containing 1 (SARM1) is an inducible NADase that localizes to mitochondria throughout neurons and senses metabolic changes that occur after injury. Minimal proteomic changes are...
2.
Byrnes A, Dominguez S, Yen C, Laufer B, Foreman O, Reichelt M, et al.
Mol Ther Nucleic Acids
. 2023 Jun;
32:773-793.
PMID: 37346977
Antisense oligonucleotide (ASO) therapeutics are being investigated for a broad range of neurological diseases. While ASOs have been effective in the clinic, improving productive ASO internalization into target cells remains...
3.
Sarode A, Fan Y, Byrnes A, Hammel M, Hura G, Fu Y, et al.
Nanoscale Adv
. 2022 Sep;
4(9):2107-2123.
PMID: 36133441
Lipid nanoparticles (LNPs) are gaining traction in the field of nucleic acid delivery following the success of two mRNA vaccines against COVID-19. As one of the constituent lipids on LNP...
4.
Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins A, Shi X, Stein J, et al.
Neuron
. 2019 Jul;
103(5):785-801.e8.
PMID: 31303374
We performed RNA sequencing on 40,000 cells to create a high-resolution single-cell gene expression atlas of developing human cortex, providing the first single-cell characterization of previously uncharacterized cell types, including...
5.
Swarup V, Hinz F, Rexach J, Noguchi K, Toyoshiba H, Oda A, et al.
Nat Med
. 2018 Dec;
25(1):152-164.
PMID: 30510257
Identifying the mechanisms through which genetic risk causes dementia is an imperative for new therapeutic development. Here, we apply a multistage, systems biology approach to elucidate the disease mechanisms in...
6.
Hinz F, Geschwind D
Cold Spring Harb Perspect Biol
. 2016 Dec;
9(4).
PMID: 27940516
Neurodegenerative dementias are clinically heterogeneous, progressive diseases with frequently overlapping symptoms, such as cognitive impairments and behavior and movement deficits. Although a majority of cases appear to be sporadic, there...
7.
Huffman L, Hinz F, Wojcik S, Aubin-Horth N, Hofmann H
Gen Comp Endocrinol
. 2014 Mar;
212:106-13.
PMID: 24662391
Neuropeptides modulate many aspects of behavior and physiology in a broad range of animals. Arginine vasotocin (AVT) is implicated in mediating social behavior in teleost fish, although its specific role...
8.
Hinz F, Aizenberg M, Tushev G, Schuman E
J Neurosci
. 2013 Sep;
33(39):15382-7.
PMID: 24068805
The larval zebrafish is a model organism to study the neural circuitry underlying behavior. There exist, however, few examples of robust long-term memory. Here we describe a simple, unrestrained associative...
9.
Tom Dieck S, Muller A, Nehring A, Hinz F, Bartnik I, Schuman E, et al.
Curr Protoc Cell Biol
. 2012 Sep;
Chapter 7:7.11.1-7.11.29.
PMID: 22968844
Fluorescent labeling of proteins by genetically encoded fluorescent protein tags has enabled an enhanced understanding of cell biological processes but is restricted to the analysis of a limited number of...
10.
Hinz F, Dieterich D, Tirrell D, Schuman E
ACS Chem Neurosci
. 2012 Feb;
3(1):40-49.
PMID: 22347535
Protein expression in the nervous system undergoes regulated changes in response to changes in behavioral states, in particular long-term memory formation. Recently, methods have been developed (BONCAT and FUNCAT), which...