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Finn C Nielsen

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Articles 104
Citations 4104
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Recent Articles
11.
Zamani M, Gronhoj C, Jensen D, Carlander A, Agander T, Kiss K, et al.
Eur J Cancer . 2020 May; 134:52-59. PMID: 32460181
Background: The objectives of this study were to investigate the incidence of high-risk genotypes of human papillomavirus (HPV) in tumours of patients with oropharyngeal squamous cell carcinoma (OPSCC) during an...
12.
Zhang H, Ahearn T, Lecarpentier J, Barnes D, Beesley J, Qi G, et al.
Nat Genet . 2020 May; 52(6):572-581. PMID: 32424353
Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls,...
13.
Feng H, Gusev A, Pasaniuc B, Wu L, Long J, Abu-Full Z, et al.
Genet Epidemiol . 2020 Mar; 44(5):442-468. PMID: 32115800
Previous transcriptome-wide association studies (TWAS) have identified breast cancer risk genes by integrating data from expression quantitative loci and genome-wide association studies (GWAS), but analyses of breast cancer subtype-specific associations...
14.
Fachal L, Aschard H, Beesley J, Barnes D, Allen J, Kar S, et al.
Nat Genet . 2020 Jan; 52(1):56-73. PMID: 31911677
Genome-wide association studies have identified breast cancer risk variants in over 150 genomic regions, but the mechanisms underlying risk remain largely unknown. These regions were explored by combining association analysis...
15.
Dimopoulou C, Lundgren J, Sundal J, Ullum H, Aukrust P, Nielsen F, et al.
J Hum Genet . 2019 Dec; 65(3):325-335. PMID: 31873220
Behçet disease (BD) is an immune-mediated disease. The cause of BD remains unknown, but the existence of multiple pathological pathways is suspected, including different genetic factors. Polymorphisms in ERAP1 gene...
16.
Qian F, Rookus M, Leslie G, Risch H, Greene M, Aalfs C, et al.
Br J Cancer . 2019 Jun; 121(2):180-192. PMID: 31213659
Background: Height and body mass index (BMI) are associated with higher ovarian cancer risk in the general population, but whether such associations exist among BRCA1/2 mutation carriers is unknown. Methods:...
17.
Ferreira M, Gamazon E, Al-Ejeh F, Aittomaki K, Andrulis I, Anton-Culver H, et al.
Nat Commun . 2019 Apr; 10(1):1741. PMID: 30988301
Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue and immune...
18.
Ahlborn L, Rohrberg K, Gabrielaite M, Tuxen I, Yde C, Spanggaard I, et al.
Oncotarget . 2019 Mar; 10(14):1388-1398. PMID: 30858924
Purpose: Access to genomic tumor material is required to select patients for targeted therapies. However, tissue biopsies are not always feasible and therefore circulating cell-free DNA (cfDNA) has emerged as...
19.
Brieghel C, Kinalis S, Yde C, Schmidt A, Jonson L, Andersen M, et al.
Haematologica . 2018 Dec; 104(4):789-796. PMID: 30514802
In chronic lymphocytic leukemia, mutations and deletion of chromosome 17p are well-characterized biomarkers associated with poor progression-free and overall survival following chemoimmunotherapy. Patients harboring low burden mutations with variant allele...
20.
Qian F, Wang S, Mitchell J, McGuffog L, Barrowdale D, Leslie G, et al.
J Natl Cancer Inst . 2018 Oct; 111(4):350-364. PMID: 30312457
Background: BRCA1/2 mutations confer high lifetime risk of breast cancer, although other factors may modify this risk. Whether height or body mass index (BMI) modifies breast cancer risk in BRCA1/2...