Filippo Zambelli
Overview
Explore the profile of Filippo Zambelli including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
275
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0
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Recent Articles
11.
Vergaro P, Tiscornia G, Zambelli F, Rodriguez A, Santalo J, Vassena R
Reprod Biomed Online
. 2020 Oct;
42(1):26-38.
PMID: 33051136
Research Question: Which are the early compartment-specific transcriptional responses of the trophoblast and the endometrial epithelium throughout early attachment during implantation? Design: An endometrial epithelium proxy (cell line Ishikawa) was...
12.
Almansa-Ordonez A, Bellido R, Vassena R, Barragan M, Zambelli F
Biology (Basel)
. 2020 Sep;
9(9).
PMID: 32899860
Mitochondria are fundamental organelles in eukaryotic cells that provide ATP through oxidative phosphorylation. During this process, reactive oxygen species (ROS) are produced, and an imbalance in their concentrations can induce...
13.
Keller A, Tilleman L, Dziedzicka D, Zambelli F, Sermon K, Van Nieuwerburgh F, et al.
Sci Rep
. 2019 Oct;
9(1):14844.
PMID: 31619727
Human pluripotent stem cells (hPSCs) have significant levels of low-grade genetic mosaicism, which commonly used techniques fail to detect in bulk DNA. These copy number variations remain a hurdle for...
14.
Torra-Massana M, Cornet-Bartolome D, Barragan M, Durban M, Ferrer-Vaquer A, Zambelli F, et al.
Hum Reprod
. 2019 Jul;
34(8):1494-1504.
PMID: 31347677
Study Question: Are phospholipase C zeta 1 (PLCZ1) mutations associated with fertilization failure (FF) after ICSI? Summary Answer: New mutations in the PLCZ1 sequence are associated with FFs after ICSI....
15.
Zambelli F, Mertens J, Dziedzicka D, Sterckx J, Markouli C, Keller A, et al.
Stem Cell Reports
. 2018 Jun;
11(1):102-114.
PMID: 29910126
In this study, we deep-sequenced the mtDNA of human embryonic and induced pluripotent stem cells (hESCs and hiPSCs) and their source cells and found that the majority of variants pre-existed...
16.
Keller A, Dziedzicka D, Zambelli F, Markouli C, Sermon K, Spits C, et al.
Hum Reprod Update
. 2018 Jan;
24(2):162-175.
PMID: 29377992
Background: Human pluripotent stem cell (hPSC) lines are known to have a bias in their differentiation. This gives individual cell lines a propensity to preferentially differentiate towards one germ layer...
17.
18.
Zambelli F, Vancampenhout K, Daneels D, Brown D, Mertens J, Van Dooren S, et al.
Eur J Hum Genet
. 2017 Aug;
25(11):1229-1236.
PMID: 28832570
Massive parallel sequencing (MPS) can accurately quantify mitochondrial DNA (mtDNA) single nucleotide variants (SNVs), but no MPS methods are currently validated to simultaneously and accurately establish the breakpoints and frequency...
19.
Jacobs K, Zambelli F, Mertzanidou A, Smolders I, Geens M, Nguyen H, et al.
Stem Cell Reports
. 2016 Mar;
6(3):330-41.
PMID: 26923824
Human embryonic stem cells (hESC) show great promise for clinical and research applications, but their well-known proneness to genomic instability hampers the development to their full potential. Here, we demonstrate...
20.
Galletti M, Cantoni S, Zambelli F, Valente S, Palazzini M, Manes A, et al.
Biochem Pharmacol
. 2014 Jul;
91(2):181-90.
PMID: 25063234
Pulmonary Arterial Hypertension (PAH) is a rare and devasting condition characterized by elevated pulmonary vascular resistance and pulmonary artery pressure leading to right-heart failure and premature death. Pathologic alterations in...