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Fernando Rodrigues-Lima

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Articles 103
Citations 1101
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Recent Articles
1.
Zhou H, Xiang W, Zhou G, Rodrigues-Lima F, Guidez F, Wang L
Med Oncol . 2024 Dec; 42(1):23. PMID: 39644425
Despite significant advancements in the research of the pathogenesis mechanisms of Myelodysplastic Neoplasm (MDS) in recent years, there are still many gaps to fill. The advancement of metabolomics studies has...
2.
Zhou Q, Zhang J, Zhang J, Liang S, Cai D, Xiao H, et al.
Biol Direct . 2024 Jan; 19(1):6. PMID: 38178263
Background: The outcome of Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) remain dismal despite the development of treatment. Targeted therapy is gaining more and more attention in improving prognosis....
3.
Delabar J, Gomes M, Fructuoso M, Sarrazin N, George N, Fleary-Roberts N, et al.
Eur J Med Chem . 2024 Jan; 265:116098. PMID: 38171148
Overexpression of the chromosome 21 DYRK1A gene induces morphological defects and cognitive impairments in individuals with Down syndrome (DS) and in DS mice models. Aging neurons of specific brain regions...
4.
de Thonel A, Ahlskog J, Daupin K, Dubreuil V, Berthelet J, Chaput C, et al.
Nat Commun . 2023 Sep; 14(1):6067. PMID: 37770591
No abstract available.
5.
Schator D, Mondino S, Berthelet J, Silvestre C, Ben Assaya M, Rusniok C, et al.
Nat Commun . 2023 Apr; 14(1):2154. PMID: 37059817
Legionella pneumophila replicates intracellularly by secreting effectors via a type IV secretion system. One of these effectors is a eukaryotic methyltransferase (RomA) that methylates K14 of histone H3 (H3K14me3) to...
6.
Montalban E, Walle R, Castel J, Ansoult A, Hassouna R, Foppen E, et al.
Biol Psychiatry . 2023 Feb; 94(5):424-436. PMID: 36805080
Background: A large body of evidence highlights the importance of genetic variants in the development of psychiatric and metabolic conditions. Among these, the TaqIA polymorphism is one of the most...
7.
Boy M, Bisio V, Zhao L, Guidez F, Schell B, Lereclus E, et al.
Nat Commun . 2023 Feb; 14(1):588. PMID: 36737440
Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders, representing high risk of progression to acute myeloid leukaemia, and frequently associated to somatic mutations, notably in the epigenetic regulator TET2. Natural Killer...
8.
de Thonel A, Ahlskog J, Daupin K, Dubreuil V, Berthelet J, Chaput C, et al.
Nat Commun . 2022 Nov; 13(1):7002. PMID: 36385105
Patients carrying autosomal dominant mutations in the histone/lysine acetyl transferases CBP or EP300 develop a neurodevelopmental disorder: Rubinstein-Taybi syndrome (RSTS). The biological pathways underlying these neurodevelopmental defects remain elusive. Here,...
9.
Villares M, Lourenco N, Berthelet J, Lamotte S, Regad L, Medjkane S, et al.
Commun Biol . 2022 Nov; 5(1):1253. PMID: 36380082
Theileria parasites are responsible for devastating cattle diseases, causing major economic losses across Africa and Asia. Theileria spp. stand apart from other apicomplexa parasites by their ability to transform host...
10.
Nian Q, Li J, Han Z, Liang Q, Liu M, Yang C, et al.
Biomed Pharmacother . 2022 Sep; 153:113519. PMID: 36076604
Secreted protein acidic and rich in cysteine (SPARC), also known as osteonectin or BM-40, is a matricellular protein involved in several biological processes including cell adhesion, growth factor availability, extracellular...