Fernando de C da Silva
Overview
Explore the profile of Fernando de C da Silva including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
239
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Recent Articles
1.
de Jesus I, Baptista de Pontes J, Paschoalin V, de C da Silva F, Ferreira V
ACS Omega
. 2025 Feb;
10(4):4163-4169.
PMID: 39926496
An environmentally friendly, cheap, and scalable protocol for direct lawsone O-alkylation employing different alcohols using acid chitosan (CS-SOH) as a heterogeneous organocatalyst is described herein for the first time. A...
2.
Rubini-Dias L, Fernandes T, de Souza M, Hottz D, Arruda A, Borges A, et al.
Biomedicines
. 2025 Jan;
12(12.
PMID: 39767822
Pyruvate kinase M2, a central regulator of cancer cell metabolism, has garnered significant attention as a promising target for disrupting the metabolic adaptability of tumor cells. This study explores the...
3.
Costa D, Froes T, Mendes M, Forezi L, Ferreira V, Castilho M, et al.
Curr Top Med Chem
. 2024 Aug;
24(24):2161-2171.
PMID: 39136508
Background: This study investigates the potential of eleven 1H-1,2,3-triazol-1,4-naphthoquinone conjugates as virulence factor inhibitors (like Pyocyanin) and their affinity for PhzM, a crucial enzyme for Pyocyanin biosynthesis in infections. Methods:...
4.
Borges A, de Andrade Borges A, Ouverney G, Arruda A, Arruda A, Ribeiro A, et al.
Curr Med Chem
. 2024 Jun;
32(2):359-379.
PMID: 38877863
Background: Oral squamous cell carcinoma (OSCC) represents the primary form of oral cancer, posing a significant global health threat. The existing chemotherapy options are accompanied by notable side effects impacting...
5.
Gomes L, Costa E, Duarte T, Charret T, Castiglione R, Simoes R, et al.
ACS Omega
. 2024 May;
9(20):21948-21963.
PMID: 38799368
Due to the growth in the number of patients and the complexity involved in anticancer therapies, new therapeutic approaches are urgent and necessary. In this context, compounds containing the selenium...
6.
de Souza A, Dias D, Ribeiro R, Costa D, de Moraes M, Pinho D, et al.
Bioorg Med Chem
. 2024 Mar;
102:117671.
PMID: 38452407
The search for novel anticancer drugs is essential to expand treatment options, overcome drug resistance, reduce toxicity, promote innovation, and tackle the economic impact. The importance of these studies lies...
7.
Gomes L, Costa E, Duarte T, Kohler M, Rodrigues B, Ferreira V, et al.
RSC Adv
. 2023 Nov;
13(49):34852-34865.
PMID: 38035251
This study presents a comprehensive analysis encompassing the synthesis, structural elucidation, photophysical behavior, and electrochemical properties of a novel series of chalcogen-naphthoquinone-1,2,3-triazole hybrids. Employing a meticulously designed protocol, the synthesis...
8.
Forezi L, Ferreira P, de Carvalho A, de C da Silva F, Ferreira V
Curr Top Med Chem
. 2023 May;
23(11):957-969.
PMID: 37198981
Pharmaceutical chemistry has many industrial processes that must be studied and adapted to a new reality where the environment must be the focus of all production chains. Thus, new technologies...
9.
Borges A, de Souza M, da Fonseca A, Wermelinger G, Ribeiro R, Amaral A, et al.
Molecules
. 2023 Jan;
28(1).
PMID: 36615502
Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, accounting for approximately 90% of all oral cancers, and is the eighth most common cancer in men. Cisplatin and...
10.
Dos Santos J, Ribeiro R, Faria J, L Bello M, Lima C, Pauli F, et al.
J Bioenerg Biomembr
. 2022 Sep;
54(5-6):227-239.
PMID: 36070071
The P2X7 receptor (P2X7R) is an ion channel that promotes the passage of ions through the membrane through brief stimulation once activated by ATP, its endogenous opener. However, prolonged stimulation...