Fergus G Earley
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Explore the profile of Fergus G Earley including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
14
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Recent Articles
1.
Korona D, Dirnberger B, Giachello C, Queiroz R, Popovic R, Muller K, et al.
Elife
. 2022 May;
11.
PMID: 35575460
nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that represent a target for insecticides. Peptide neurotoxins are known to block nAChRs by binding to their target subunits, however, a better...
2.
Zhou C, Cheng J, Beadle R, Earley F, Li Z, Maienfisch P
Bioorg Med Chem
. 2020 May;
28(11):115509.
PMID: 32354673
The application of a carbon-silicon bioisosteric replacement strategy to find new acaricides with improved properties led to the discovery of Sila-Cyflumetofen 6B, a novel and highly potent acaricide. The essential...
3.
Chambers C, Cutler P, Huang Y, Goodchild J, Blythe J, Wang C, et al.
FEBS Lett
. 2019 May;
593(12):1336-1350.
PMID: 31102259
The insecticidal effects of ω-hexatoxin-Hv1a, κ-hexatoxin-Hv1c and ω/κ-hexatoxin-Hv1h are currently attributed to action at calcium and potassium channels. By characterizing the binding of these toxins to neuronal membranes, we show...