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Felix Olale

Explore the profile of Felix Olale including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 760
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Recent Articles
1.
Panizzi J, Becker-Heck A, Castleman V, Al-Mutairi D, Liu Y, Loges N, et al.
Nat Genet . 2012 May; 44(6):714-9. PMID: 22581229
Cilia are essential for fertilization, respiratory clearance, cerebrospinal fluid circulation and establishing laterality. Cilia motility defects cause primary ciliary dyskinesia (PCD, MIM244400), a disorder affecting 1:15,000-30,000 births. Cilia motility requires...
2.
Auman H, Coleman H, Riley H, Olale F, Tsai H, Yelon D
PLoS Biol . 2007 Feb; 5(3):e53. PMID: 17311471
Developing organs acquire a specific three-dimensional form that ensures their normal function. Cardiac function, for example, depends upon properly shaped chambers that emerge from a primitive heart tube. The cellular...
3.
Obara T, Mangos S, Liu Y, Zhao J, Wiessner S, Kramer-Zucker A, et al.
J Am Soc Nephrol . 2006 Sep; 17(10):2706-18. PMID: 16943304
Polycystin-2 functions as a cation-permeable transient receptor potential ion channel in kidney epithelial cells and when mutated results in human autosomal dominant polycystic kidney disease. For further exploration of the...
4.
Kramer-Zucker A, Olale F, Haycraft C, Yoder B, Schier A, Drummond I
Development . 2005 Mar; 132(8):1907-21. PMID: 15790966
Cilia, as motile and sensory organelles, have been implicated in normal development, as well as diseases including cystic kidney disease, hydrocephalus and situs inversus. In kidney epithelia, cilia are proposed...
5.
Cheng S, Olale F, Brivanlou A, Schier A
PLoS Biol . 2004 Feb; 2(2):E30. PMID: 14966532
Members of the EGF-CFC family play essential roles in embryonic development and have been implicated in tumorigenesis. The TGFbeta signals Nodal and Vg1/GDF1, but not Activin, require EGF-CFC coreceptors to...
6.
Cheng S, Olale F, Bennett J, Brivanlou A, Schier A
Genes Dev . 2003 Jan; 17(1):31-6. PMID: 12514096
The TGF-beta signals Nodal, Activin, GDF1, and Vg1 have been implicated in mesoderm induction and left-right patterning. Nodal and Activin both activate Activin receptors, but only Nodal requires EGF-CFC coreceptors...