Felice Frey
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Explore the profile of Felice Frey including associated specialties, affiliations and a list of published articles.
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7
Citations
156
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Recent Articles
1.
Frey F, Sandakly J, Ghannam M, Doueiry C, Hugosson F, Berlandi J, et al.
eNeuro
. 2022 Apr;
9(2).
PMID: 35396259
Ten-eleven translocation (TET) proteins are crucial epigenetic regulators highly conserved in multicellular organisms. TETs' enzymatic function in demethylating 5-methyl cytosine in DNA is required for proper development and TETs are...
2.
Chaouch A, Berlandi J, Chen C, Frey F, Badini S, Harutyunyan A, et al.
Mol Cell
. 2021 Nov;
81(23):4876-4890.e7.
PMID: 34739871
Histone H3.3 lysine-to-methionine substitutions K27M and K36M impair the deposition of opposing chromatin marks, H3K27me3/me2 and H3K36me3/me2. We show that these mutations induce hypotrophic and disorganized eyes in Drosophila eye...
3.
Ismail J, Ghannam M, Al Outa A, Frey F, Shirinian M
Epigenetics
. 2020 May;
15(11):1139-1150.
PMID: 32419604
Ten-eleven Translocation (TET) proteins have emerged as a family of epigenetic regulators that are important during development and have been implicated in various types of cancers. TET is a highly...
4.
Boileau M, Shirinian M, Gayden T, Harutyunyan A, Chen C, Mikael L, et al.
Nat Commun
. 2019 Jun;
10(1):2891.
PMID: 31253791
Our ability to manage acute myeloid leukemia (AML) is limited by our incomplete understanding of the epigenetic disruption central to leukemogenesis, including improper histone methylation. Here we examine 16 histone...
5.
Ismail J, Badini S, Frey F, Abou-Kheir W, Shirinian M
Front Cell Neurosci
. 2019 Jun;
13:252.
PMID: 31213988
Ten-Eleven Translocation (TET) proteins are important epigenetic regulators that play a key role in development and are frequently deregulated in cancer. has a single homologous Tet gene () that is...
6.
Frey F, Sheahan T, Finkl K, Stoehr G, Mann M, Benda C, et al.
Genes Dev
. 2016 May;
30(9):1116-27.
PMID: 27151979
Polycomb group (PcG) protein complexes repress transcription by modifying target gene chromatin. In Drosophila, this repression requires association of PcG protein complexes with cis-regulatory Polycomb response elements (PREs), but the...
7.
Brechmann M, Mock T, Nickles D, Kiessling M, Weit N, Breuer R, et al.
Immunity
. 2012 Oct;
37(4):697-708.
PMID: 23084358
Signal transduction to nuclear factor-kappa B (NF-κB) involves multiple kinases and phosphorylated target proteins, but little is known about signal termination by dephosphorylation. By RNAi screening, we have identified protein...