Fei Xavier Chen
Overview
Explore the profile of Fei Xavier Chen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
743
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Dai P, Tan Y, Luo Y, Liu T, Huang Y, Shang Y, et al.
Mol Cell
. 2025 Mar;
PMID: 40049162
In adaptive immunity, transcription-coupled damage (TCD) is introduced into antibody genes by activation-induced cytidine deaminase (AID) to diversify antibody repertoire. However, the coordination between transcription and DNA damage/repair remains elusive....
2.
Cheng Z, Zhang S, Wang Z, Song A, Gao C, Song J, et al.
Cell Metab
. 2025 Mar;
PMID: 40037360
Pathogenic bacterial persistence enables survival during antibiotic treatment, leading to treatment failure and recurrent infections, yet its underlying mechanisms remain unclear. Here, we reveal that glyoxylate, a metabolite originally evolved...
3.
Li Y, Fischer P, Wang M, Zhou Q, Song A, Yuan R, et al.
Cell Res
. 2025 Feb;
PMID: 40016598
The spliceosome, a highly dynamic macromolecular assembly, catalyzes the precise removal of introns from pre-mRNAs. Recent studies have provided comprehensive structural insights into the step-wise assembly, catalytic splicing and final...
4.
Liu W, Deng L, Wang M, Liu X, OuYang X, Wang Y, et al.
Mol Cell
. 2025 Feb;
85(5):929-947.e10.
PMID: 40015272
The PIWI-interacting RNA (piRNA) pathway plays a crucial role in protecting animal germ cells by repressing transposons. However, the mechanism of piRNA-guided heterochromatin formation and its relationship to transcriptional termination...
5.
Tao B, Wang Z, Wang X, Song A, Liu J, Wang J, et al.
J Clin Invest
. 2025 Feb;
PMID: 39998882
Genome-wide human genetic studies have identified inherited cis-regulatory loci variants that predispose to cancers. However, the mechanisms by which these germline variants influence cancer progression, particularly through gene expression and...
6.
Huang Z, Diehl F, Wang M, Li Y, Song A, Chen F, et al.
Mol Cell
. 2025 Feb;
85(4):802-814.e12.
PMID: 39947183
Cells tightly regulate ribosome homeostasis to adapt to changing environments. Ribosomes are degraded during stress, but the mechanisms responsible remain unclear. Here, we show that starvation induces the selective depletion...
7.
Xu C, Li C, Chen J, Xiong Y, Qiao Z, Fan P, et al.
Nature
. 2025 Jan;
638(8049):E1.
PMID: 39833484
No abstract available.
8.
Fan P, Shang X, Song A, Chen S, Mao R, Ma J, et al.
Nat Chem Biol
. 2025 Jan;
PMID: 39809894
Chromatin and transcription regulators are critical to defining cell identity through shaping epigenetic and transcriptional landscapes, with their misregulation being closely linked to oncogenesis. Pharmacologically targeting these regulators, particularly the...
9.
Du Y, Wang Y, Bao Q, Xu X, Xu C, Wang S, et al.
Adv Mater
. 2024 Dec;
37(6):e2412815.
PMID: 39726096
While tumor organoids have revolutionized cancer research by recapitulating the cellular architecture and behaviors of real tumors in vitro, their lack of functional vasculature hinders their attainment of full physiological...
10.
Yang Y, Liao J, Pan Z, Meng J, Zhang L, Shi W, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(5):e2413103.
PMID: 39656925
Inhibitors targeting cyclin-dependent kinases 4 and 6 (CDK4/6) to block cell cycle progression have been effective in treating hormone receptor-positive breast cancer, but triple-negative breast cancer (TNBC) remains largely resistant,...