Federica Belluti
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Explore the profile of Federica Belluti including associated specialties, affiliations and a list of published articles.
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85
Citations
756
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Recent Articles
1.
Orioli R, Belluti F, Gobbi S, Rampa A, Bisi A
Molecules
. 2024 Aug;
29(15).
PMID: 39124919
The main feature of neurodegenerative diseases, including Alzheimer's disease, is the network of complex and not fully recognized neuronal pathways and targets involved in their onset and progression. The therapeutic...
2.
Elzahhar P, Orioli R, Hassan N, Gobbi S, Belluti F, Labib H, et al.
Eur J Med Chem
. 2024 Jan;
266:116138.
PMID: 38219658
As a new approach to the management of inflammatory disorders, a series of chromone-based derivatives containing a (carbamate)hydrazone moiety was designed and synthesized. The compounds were assessed for their ability...
3.
Gobbi S, Martini S, Rozza R, Spinello A, Caciolla J, Rampa A, et al.
Molecules
. 2023 Apr;
28(7).
PMID: 37049810
Despite the significant outcomes attained by scientific research, breast cancer (BC) still represents the second leading cause of death in women. Estrogen receptor-positive (ER+) BC accounts for the majority of...
4.
De Lorenzi E, Seghetti F, Tarozzi A, Pruccoli L, Contardi C, Serra M, et al.
Eur J Med Chem
. 2023 Mar;
252:115297.
PMID: 36996713
Simultaneous modulation of multifaceted toxicity arising from neuroinflammation, oxidative stress, and mitochondrial dysfunction represents a valuable therapeutic strategy to tackle Alzheimer's disease. Among the significant hallmarks of the disorder, Aβ...
5.
Hitting drug-resistant malaria infection with triazole-linked flavonoid-chloroquine hybrid compounds
Seghetti F, Belluti F, Rampa A, Gobbi S, Legac J, Parapini S, et al.
Future Med Chem
. 2023 Jan;
14(24):1865-1880.
PMID: 36622669
: Malaria represents the major parasitic disease in tropical regions, and the development of new potent drugs is of pivotal importance. In this study, a series of hybrid molecules were ...
6.
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy
Caciolla J, Martini S, Spinello A, Belluti F, Bisi A, Zaffaroni N, et al.
Eur J Med Chem
. 2022 Oct;
244:114802.
PMID: 36240547
The most frequently diagnosed breast cancer (BC) type in women expresses estrogen receptor (ER) and depends on estrogens for its growth, being classified as ER positive (ER+). The gold standard...
7.
Bisi A, Feoli A, Trezza A, Viejo L, Formaggio F, Bartolini M, et al.
Bioorg Chem
. 2022 Sep;
129:106152.
PMID: 36155094
The complexity of neurodegenerative diseases, among which Alzheimer's disease plays a pivotal role, poses one of the tough therapeutic challenges of present time. In this perspective, a multitarget approach appears...
8.
Rossi M, Cappadone C, Picone G, Bisi A, Farruggia G, Belluti F, et al.
Molecules
. 2022 Jun;
27(12).
PMID: 35744886
Osteosarcoma (OS) is a malignant disease characterized by poor prognosis due to a high incidence of metastasis and chemoresistance. Recently, Licochalcone A (Lic-A) has been reported as a promising agent...
9.
De Lorenzi E, Franceschini D, Contardi C, Di Martino R, Seghetti F, Serra M, et al.
Int J Mol Sci
. 2022 Apr;
23(8).
PMID: 35457197
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is not restricted to the neuronal compartment but includes important interactions with immune cells, including microglia. Protein aggregates, common pathological hallmarks...
10.
Seghetti F, Gobbi S, Belluti F, Rampa A, Bisi A
Curr Med Chem
. 2021 Nov;
29(28):4796-4830.
PMID: 34781863
Pharmacological treatment of complex pathologies, such as neurodegenerative diseases still represents a major challenge, due to the networked pathways involved in their onset and progression that may require equally complex...