Farzad Izaddoustdar
Overview
Explore the profile of Farzad Izaddoustdar including associated specialties, affiliations and a list of published articles.
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8
Citations
196
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0
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Recent Articles
1.
Lakin R, Polidovitch N, Yang S, Parikh M, Liu X, Debi R, et al.
Cardiovasc Res
. 2023 Sep;
119(16):2607-2622.
PMID: 37713664
Aims: Endurance exercise is associated with an increased risk of atrial fibrillation (AF). We previously established that adverse atrial remodelling and AF susceptibility induced by intense exercise in mice require...
2.
Oh Y, Yang S, Liu X, Jana S, Izaddoustdar F, Gao X, et al.
Front Physiol
. 2021 Jan;
11:605671.
PMID: 33424629
Atrial Fibrillation (AF) is the most common supraventricular tachyarrhythmia that is typically associated with cardiovascular disease (CVD) and poor cardiovascular health. Paradoxically, endurance athletes are also at risk for AF....
3.
Lakin R, Polidovitch N, Yang S, Guzman C, Gao X, Wauchop M, et al.
J Mol Cell Cardiol
. 2019 Feb;
129:165-173.
PMID: 30796945
Intense endurance exercise is linked to atrial fibrillation (AF). We established previously that interventions that simultaneously interfere with TNFα signaling, mediated via both the enzymatically liberated soluble and membrane-bound forms...
4.
Lakin R, Guzman C, Izaddoustdar F, Polidovitch N, Goodman J, Backx P
Front Physiol
. 2018 Aug;
9:841.
PMID: 30061838
New And Noteworthy: -No previous mouse studies have compared the effects of forced and voluntary exercise on the heart function and its modulation by the autonomic nervous system (ANS).-Both voluntary...
5.
Laksman Z, Wauchop M, Lin E, Protze S, Lee J, Yang W, et al.
Sci Rep
. 2017 Jul;
7(1):5268.
PMID: 28706272
Since current experimental models of Atrial Fibrillation (AF) have significant limitations, we used human embryonic stem cells (hESCs) to generate an atrial-specific tissue model of AF for pharmacologic testing. We...
6.
Aschar-Sobbi R, Izaddoustdar F, Korogyi A, Wang Q, Farman G, Yang F, et al.
Nat Commun
. 2015 Jan;
6:6018.
PMID: 25598495
Atrial fibrillation (AF) is the most common supraventricular arrhythmia that, for unknown reasons, is linked to intense endurance exercise. Our studies reveal that 6 weeks of swimming or treadmill exercise...
7.
Rajapurohitam V, Izaddoustdar F, Martinez-Abundis E, Karmazyn M
Cell Signal
. 2012 Aug;
24(12):2283-90.
PMID: 22917533
Leptin, a product of the obesity gene, has been shown to produce cardiac hypertrophy. Although leptin's mechanism of action is poorly understood activation of the RhoA/ROCK pathway has been proposed...
8.
Rose R, Sellan M, Simpson J, Izaddoustdar F, Cifelli C, Panama B, et al.
Circ Arrhythm Electrophysiol
. 2011 Jul;
4(5):733-42.
PMID: 21747058
Background: Chronic iron overload (CIO) is associated with blood disorders such as thalassemias and hemochromatosis. A major prognostic indicator of survival in patients with CIO is iron-mediated cardiomyopathy characterized by...