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F W Jacobsen

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Articles 26
Citations 418
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Recent Articles
1.
Biere A, Wood S, Wypych J, Steavenson S, Jiang Y, Anafi D, et al.
J Biol Chem . 2000 Aug; 275(44):34574-9. PMID: 10942772
Parkinson's disease (PD) is a neurodegenerative disorder that is pathologically characterized by the presence of intracytoplasmic Lewy bodies. Recently, two point mutations in alpha-synuclein were found to be associated with...
2.
Veiby O, Jacobsen F, Cui L, Lyman S, Jacobsen S
J Immunol . 1996 Oct; 157(7):2953-60. PMID: 8816402
The recently cloned fIt3 ligand (FL) potently enhances hemopoietic growth factor-induced growth of primitive hemopoietic progenitors. In agreement with previous reports, we found FL alone to be a weak mitogen...
3.
Jacobsen F, Veiby O, Stokke T, Jacobsen S
J Immunol . 1996 Aug; 157(3):1193-9. PMID: 8757625
It is well established that TNF-alpha can induce apoptosis in many normal and transformed cell types. The effects of TNF-alpha on cytokine-induced proliferation and differentiation of normal hematopoietic progenitors have...
4.
Sandnes D, Jacobsen F, Refsnes M, Christoffersen T
Pharmacol Toxicol . 1996 Jul; 79(1):15-22. PMID: 8841091
Addition of 8-bromo-adenosine 3',5'-cyclic monophosphate (8-bromo-cAMP) or 8-(4-chlorophenylthio)-adenosine 3',5'-cyclic monophosphate (8-CPT-cAMP) to hepatocytes at the time of plating enhanced the acquisition of beta-adrenoceptors that occurs spontaneously upon culturing as primary...
5.
Jacobsen F, Stokke T, Jacobsen S
Blood . 1995 Oct; 86(8):2957-66. PMID: 7579388
In contrast with the extensively characterized effects of transforming growth factor-beta (TGF-beta) on proliferation and differentiation of hematopoietic progenitors, little is known about the effects of TGF-beta on viability of...
6.
Jacobsen F, Keller J, Ruscetti F, Veiby O, Jacobsen S
Exp Hematol . 1995 Aug; 23(9):990-5. PMID: 7543420
The present studies have investigated, for the first time, the synergistic effects of interleukin-4 (IL-4) and IL-11 on the growth of single murine bone marrow progenitor cells. These studies suggest...
7.
Jacobsen F, Dubois C, Rusten L, Veiby O, Jacobsen S
J Immunol . 1995 Apr; 154(8):3732-41. PMID: 7535812
TNF-alpha is a pleiotropic cytokine with stimulatory as well as inhibitory effects on hematopoiesis. We have previously demonstrated that TNF-alpha directly inhibits CSF-induced proliferation of primitive murine lineage-negative bone marrow...
8.
Tasken K, Jacobsen F, Eikvar L, Hansson V, Haugen T
Biochim Biophys Acta . 1995 Feb; 1260(3):269-75. PMID: 7873600
In the present study, we have examined regulatory effects of protein kinase A and protein kinase C activation by 8-CPTcAMP and TPA, respectively, on mRNAs for various G protein alpha-subunits...
9.
Jacobsen F, Rothe M, Rusten L, Goeddel D, Smeland E, Veiby O, et al.
Proc Natl Acad Sci U S A . 1994 Oct; 91(22):10695-9. PMID: 7524102
Biological effects of tumor necrosis factor alpha (TNF-alpha) are mediated through two cell surface receptors, the 55-kDa TNF receptor and the 75-kDa TNF receptor. The present study investigated the relative...
10.
Fahlman C, Jacobsen F, Veiby O, McNiece I, Blomhoff H, Jacobsen S
Blood . 1994 Sep; 84(5):1528-33. PMID: 7520777
Tumor necrosis factor-alpha (TNF-alpha) is a bifunctional regulator of hematopoiesis, and its cellular responses are mediated by two distinct cell surface receptors. TNF-alpha generally inhibits the growth of primitive murine...