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F Sauriol

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Articles 20
Citations 45
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Recent Articles
1.
Zamir L, Devor K, Nikolakakis A, Sauriol F
Can J Microbiol . 2011 Nov; 42(8):828-34. PMID: 22049997
3-Acetyldeoxynivalenol is the major trichothecene produced by the fungus Fusarium culmorum. Studies in vivo with F. culmorum have established the following biosynthetic precursors of 3-acetyldeoxynivalenol: isotrichool → isotrichodiol → isotrichodermin ...
2.
Sun D, Nikolakakis A, Sauriol F, Mamer O, Zamir L
Bioorg Med Chem . 2001 Aug; 9(8):1985-92. PMID: 11504635
5alpha, 7beta, 9alpha, 10beta, 13alpha-Pentahydroxy-4(20),11(12)-taxadiene derivative 1 was converted to two unprecedented 1(15-->11)abeo-taxanes and a taxane derivative with a C10-C11 double bond by Absidia coerula ATCC 10738a. A similar compound...
3.
Fouad F, Mamer O, Sauriol F, Ruhenstroth-Bauer G
Med Hypotheses . 2001 Jun; 56(6):709-23. PMID: 11399123
Intoxication and liver damage induced by carbon tetrachloride (CCl(4)), aflatoxin B1, diabetes, and subtotal partial hepatectomy (PH(90)) in rats in which approximately 90% of the total hepatic tissue mass is...
4.
Zhang J, Sauriol F, Mamer O, You X, Alaoui-Jamali M, Batist G, et al.
J Nat Prod . 2001 Apr; 64(4):450-5. PMID: 11325226
Eight minor taxanes have been identified for the first time in Taxus canadensis needles. Four of these metabolites are new taxane analogues: 7-acetyl-10-deacetyltaxol (1), 2'-acetyl-7-epi-cephalomannine (2), 10-deacetyl-10-oxo-7-epi-cephalomannine (3), and 10-acetylglycollylbaccatin...
5.
Sun D, Sauriol F, Mamer O, Zamir L
Bioorg Med Chem . 2001 Apr; 9(3):793-800. PMID: 11310614
A 4(20),11(12)-taxadiene derivative was converted to hydroxylated derivatives by Cunninghamella elegans AS3.2033 and Cunninghamella elegans var chibaensis ATCC 20230. Both microorganisms led to C-1 hydroxylations and conversion to a C-15-hydroxylated...
6.
Zhang J, Sauriol F, Mamer O, Zamir L
J Nat Prod . 2000 Aug; 63(7):929-33. PMID: 10924167
Nine minor taxanes were identified for the first time in the Canadian yew needles. Four of these metabolites are new: 5-epi-cinnamoylcanadensene (1), 2,9,10, 13-tetraacetoxy-20-cinnamoyloxy-taxa-4(5),11(12)-diene (2), 2'-acetyl-epi-taxol (3), and 9-deacetyltaxinine E...
7.
Nikolakakis A, Caron G, Cherestes A, Sauriol F, Mamer O, Zamir L
Bioorg Med Chem . 2000 Jul; 8(6):1269-80. PMID: 10896107
An efficient conversion of Taxus canadensis abundant taxane, 9-dihydro-13-acetylbaccatin III to baccatin III is described. Since the synthesis of paclitaxel from baccatin III has been reported, this work can be...
8.
Zhang J, Sauriol F, Mamer O, Zamir L
Phytochemistry . 2000 Jun; 54(2):221-30. PMID: 10872214
Systematic characterization of the taxoids in the needles of Taxus canadensis led to the discovery of seven taxanes along with three known congeners. Their structures were rigorously established by spectroscopic...
9.
Zamir L, Nikolakakis A, Sauriol F, Mamer O
J Agric Food Chem . 1999 Dec; 47(5):1823-35. PMID: 10552458
Fusarium culmorum produces two major trichothecenes, 3-acetyldeoxynivalenol and sambucinol, and some minor apotrichothecenes. It was desired to investigate if during their biosynthesis a C-11-keto intermediate was involved. To verify this...
10.
Zamir L, Nikolakakis A, Huang L, St-Pierre P, Sauriol F, Sparace S, et al.
J Biol Chem . 1999 Apr; 274(18):12269-77. PMID: 10212195
The first two oxygenation steps post-trichodiene in the biosyntheses of the trichothecenes 3-acetyldeoxynivalenol and sambucinol were investigated. The plausible intermediates 2-hydroxytrichodiene (2alpha- and 2beta-) and 12,13-epoxytrichodiene and the dioxygenated compounds...