F J KUHN
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Explore the profile of F J KUHN including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
130
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Recent Articles
1.
Greeff N, KUHN F
Biophys J
. 2000 Oct;
79(5):2434-53.
PMID: 11053121
Whole-cell gating current recording from rat brain IIA sodium channels in Xenopus oocytes was achieved using a high-expression system and a newly developed high-speed two-electrode voltage-clamp. The resulting ionic currents...
2.
KUHN F, Greeff N
J Gen Physiol
. 1999 Aug;
114(2):167-83.
PMID: 10435996
The highly charged transmembrane segments in each of the four homologous domains (S4D1-S4D4) represent the principal voltage sensors for sodium channel gating. Hitherto, the existence of a functional specialization of...
3.
Schreiner U, Hansen J, KUHN F, Knopf C
Intervirology
. 1999 Jul;
42(1):17-21.
PMID: 10393499
An epitope (HPOL) derived from the so-called thumb region of the herpes simplex virus type 1 DNA polymerase in combination with a monoclonal antibody (MAb 1051c) was tested for protein...
4.
Franz C, KUHN F, Knopf C
Virology
. 1999 Jan;
253(1):55-64.
PMID: 9887318
Herpes simplex virus DNA polymerase (HSV pol) holoenzyme consists of a large catalytic (UL30 gene product) and a small auxiliary subunit (UL42 gene product). The DNA binding of HSV pol,...
5.
KUHN F, Knopf C
J Biol Chem
. 1996 Nov;
271(46):29245-54.
PMID: 8910584
Like true DNA replicases, herpes simplex virus type 1 DNA polymerase is equipped with a proofreading 3'-5'-exonuclease. In order to assess the functional significance of conserved residues in the putative...
6.
Ensinger H, Doods H, KUHN F, Lambrecht G, Mendla K, Muller R, et al.
Life Sci
. 1993 Jan;
52(5-6):473-80.
PMID: 8441328
The ability of WAL 2014 to elicit muscarinic responses was investigated in various in vitro and in vivo models. In CHO cells transfected with human m1- or m3- receptor genes,...
7.
KUHN F, Weisse I
Lens Eye Toxic Res
. 1990 Jan;
7(3-4):667-76.
PMID: 2100185
Using light induced retinal damage in albino rats as a model, the time of occurrence of lesions was investigated by ophthalmoscopy, electroretinography and light microscopy. Changes in the electroretinogram correlated...
8.
Fugner A, Bechtel W, KUHN F, Mierau J
Arzneimittelforschung
. 1988 Oct;
38(10):1446-53.
PMID: 2461715
Epinastine (3-amino-9,13b-dihydro-1H-dibenz [c,f]imidazo[1,5-a]azepine hydrochloride, WAL 801 CL) was tested in vitro and in vivo in comparison with other H1-receptor antagonists. In the guinea pig ileum and in receptor binding studies...
9.
KUHN F, Schingnitz G, LEHR E, Montagna E, Hinzen H, Giachetti A
Arch Int Pharmacodyn Ther
. 1988 Mar;
292:13-34.
PMID: 3395164
The pharmacological effects of the novel compound WEB 1881 FU (4-amino-methyl-1-benzyl-pyrrolidine-2-one-fumarate) were investigated. The tests performed indicate that the compound has cytoprotective as well as metabolism and cognition enhancing and...
10.
DANNEBERG P, Bauer R, HOEFKE W, KUHN F, LEHR E, Walland A
Arzneimittelforschung
. 1986 Mar;
36(3A):540-51.
PMID: 3718576
Brotizolam (2-bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f]-1,2,4-triazolo [4,3-a]-1,4-diazepine, We 941, Lendormin) is a thienotriazolo-diazepine with profound sedative and hypnogenic properties. The side effects of the drug on general behavior, motocoordination, feeding pattern, body temperature, uropoietic...