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F Bernassola

Explore the profile of F Bernassola including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 944
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Recent Articles
1.
Amelio I, Bernassola F, Candi E
Semin Cancer Biol . 2020 Jul; 72:36-45. PMID: 32619506
Breast cancer is the most common cancer in women with the highest mortality among this gender. Despite treatment strategies including surgery, hormone therapy and targeted therapy have recently advanced, innovative...
2.
Sanarico A, Ronchini C, Croce A, Memmi E, Cammarata U, De Antoni A, et al.
Leukemia . 2017 Dec; 32(4):911-919. PMID: 29209041
The E3 ubiquitin ligase (E3) WWP1 is an oncogenic factor implicated in the maintenance of different types of epithelial cancers. The role of WW domain-containing E3 ubiquitin protein ligase 1...
3.
Bernassola F, Scheuerpflug C, Herr I, Krammer P, Debatin K, Melino G
Cell Death Differ . 2015 Aug; 22(9):1562. PMID: 26256517
No abstract available.
4.
Rossi M, Rotblat B, Ansell K, Amelio I, Caraglia M, Misso G, et al.
Cell Death Dis . 2014 May; 5:e1203. PMID: 24787015
Inhibition of distinct ubiquitin E3 ligases might represent a powerful therapeutic tool. ITCH is a HECT domain-containing E3 ligase that promotes the ubiquitylation and degradation of several proteins, including p73,...
5.
Celardo I, Grespi F, Antonov A, Bernassola F, Garabadgiu A, Melino G, et al.
Cell Death Dis . 2013 May; 4:e645. PMID: 23703390
p63 is a p53 family transcription factor, which besides unique roles in epithelial development, shares tumor suppressive activity with its homolog p53. The p63 gene has different transcriptional start sites,...
6.
Malatesta M, Peschiaroli A, Memmi E, Zhang J, Antonov A, Green D, et al.
Oncogene . 2012 Oct; 32(39):4721-6. PMID: 23085759
The Cullin4A (cul4A)-dependent ligase (CDL4A) E3 has been implicated in a variety of biological processes, including cell cycle progression and DNA damage response. Remarkably, CDL4A exerts its function through both...
7.
Savino R, Demartis A, Ciapponi L, Sporeno E, Toniatti C, Bernassola F, et al.
Oncol Rep . 2011 May; 4(3):485-92. PMID: 21590082
Interleukin-6 (IL-6) plays a central role in the pathogenesis of multiple myeloma, acting both as a growth and a survival factor for myeloma cells. IL-6 has been recently shown to...
8.
Dotsch V, Bernassola F, Coutandin D, Candi E, Melino G
Cold Spring Harb Perspect Biol . 2010 May; 2(9):a004887. PMID: 20484388
p73 and p63 are two homologs of the tumor suppressive transcription factor p53. Given the high degree of structural similarity shared by the p53 family members, p73 and p63 can...
9.
Bernassola F, Ciechanover A, Melino G
Cell Death Differ . 2009 Dec; 17(1):1-3. PMID: 20010850
No abstract available.
10.
Peschiaroli A, Scialpi F, Bernassola F, Pagano M, Melino G
Oncogene . 2009 Jul; 28(35):3157-66. PMID: 19581926
The transcription factor p73, a member of the p53 family, mediates cell-cycle arrest and apoptosis in response to DNA damage-induced cellular stress, acting thus as a proapoptotic gene. Similar to...