A J Malcolm
Overview
Explore the profile of A J Malcolm including associated specialties, affiliations and a list of published articles.
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123
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1352
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Recent Articles
1.
Senior P, Koh A, Yau J, Imes S, Dinyari P, Malcolm A, et al.
Diabet Med
. 2016 Apr;
34(2):204-212.
PMID: 27087519
Aims: Resuming insulin use due to waning function is common after islet transplantation. Animal studies suggest that gastrointestinal hormones, including gastrin and incretins may increase β-cell mass. We tested the...
2.
Forbes S, Oram R, Smith A, Lam A, Olateju T, Imes S, et al.
Am J Transplant
. 2016 Mar;
16(9):2704-13.
PMID: 27017888
The beta score, a composite measure of beta cell function after islet transplantation, has limited sensitivity because of its categorical nature and requires a mixed-meal tolerance test (MMTT). We developed...
3.
Hayes S, Wells S, Harake J, Henderson J, Malcolm A
J Clin Pathol
. 2005 Jun;
58(7):782-3.
PMID: 15976352
No abstract available.
4.
Lovat P, Dobson M, Malcolm A, Pearson A, Redfern C
Med Pediatr Oncol
. 2001 Jul;
36(1):135-8.
PMID: 11464866
Background: 9-cis retinoic acid (RA) is more effective than all-trans RA at inducing neuroblastoma differentiation in vitro, and has distinct biological properties with respect to its ability to promote apoptosis...
5.
Tweddle D, Malcolm A, Cole M, Pearson A, Lunec J
Am J Pathol
. 2001 Jun;
158(6):2067-77.
PMID: 11395384
This study investigated the hypothesis that p53 accumulation in neuroblastoma, in the absence of mutation, is associated with functional inactivation, which interferes with downstream mediators of p53 function. To test...
6.
Tweddle D, Malcolm A, Bown N, Pearson A, Lunec J
Cancer Res
. 2001 Feb;
61(1):8-13.
PMID: 11196202
p53 mutations are rare in neuroblastomas at diagnosis perhaps accounting for their initial response to therapy, but advanced neuroblastoma frequently relapses, and it is possible that p53 mutations develop later....
7.
Lovat P, Ranalli M, Bernassola F, Tilby M, Malcolm A, Pearson A, et al.
Med Pediatr Oncol
. 2000 Dec;
35(6):663-8.
PMID: 11107142
The RARbeta/gamma-selective retinoids fenretinide and CD437 induce caspase-dependent apoptosis but generate free radicals independently of caspases. Apoptosis, but not free radical generation, induced by these retinoids is inhibited by RARbeta/gamma-specific...
8.
Lovat P, Ranalli M, Bernassola F, Tilby M, Malcolm A, Pearson A, et al.
Int J Cancer
. 2000 Nov;
88(6):977-85.
PMID: 11093824
Retinoic acid therapy improves the survival of children with neuroblastoma and 13-cis retinoic acid now forms an important component of treatment for residual disease of stage IV neuroblastoma after chemotherapy....
9.
Lovat P, Ranalli M, Bernassola F, Piacentini M, Malcolm A, Pearson A, et al.
Exp Cell Res
. 2000 Sep;
260(1):50-60.
PMID: 11010810
Fenretinide is an effective inducer of apoptosis in many malignancies but its precise mechanism(s) of action in the induction of apoptosis in neuroblastoma is unclear. To characterize fenretinide-induced apoptosis, neuroblastoma...
10.
Hide I, Baudouin C, Murray S, Malcolm A
Skeletal Radiol
. 2000 Sep;
29(9):538-42.
PMID: 11000301
A 43-year-old man with a large ancient schwannoma of the pelvis, presenting with varicose veins, is reported. Ancient schwannoma (neurilemmoma) is a benign tumour of nerve sheath origin characterised histologically...