Ewan St J Smith
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Explore the profile of Ewan St J Smith including associated specialties, affiliations and a list of published articles.
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24
Citations
605
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Recent Articles
1.
Sokolowski D, Miclaus M, Nater A, Faykoo-Martinez M, Hoekzema K, Zuzarte P, et al.
bioRxiv
. 2024 Dec;
PMID: 39651266
The naked mole-rat (NMR; ) is a eusocial subterranean rodent with a highly unusual set of physiological traits that has attracted great interest amongst the scientific community. However, the genetic...
2.
Smith E
Osteoarthritis Cartilage
. 2023 Jul;
31(10):1275-1277.
PMID: 37460008
No abstract available.
3.
Urriola-Munoz P, Pattison L, Smith E
J Cell Physiol
. 2023 Feb;
238(4):761-775.
PMID: 36790936
The naked mole-rat (NMR, Heterocephalus glaber) is of significant interest to biogerontological research, rarely developing age-associated diseases, such as cancer. The transmembrane glycoprotein CD44 is upregulated in certain cancers and...
4.
Barker K, Higham J, Pattison L, Chessell I, Welsh F, Smith E, et al.
Am J Physiol Gastrointest Liver Physiol
. 2023 Feb;
324(4):G250-G261.
PMID: 36749569
The effective management of visceral pain is a significant unmet clinical need for those affected by gastrointestinal diseases, such as inflammatory bowel disease (IBD). The rational design of novel analgesics...
5.
Barker K, Higham J, Pattison L, Taylor T, Chessell I, Welsh F, et al.
J Physiol
. 2022 Jul;
600(16):3819-3836.
PMID: 35775903
Visceral pain is a leading cause of morbidity in gastrointestinal diseases, which is exacerbated by the gut-related side-effects of many analgesics. New treatments are needed and further understanding of the...
6.
Fatima I, Chen G, Botchkareva N, Sharov A, Thornton D, Wilkinson H, et al.
J Invest Dermatol
. 2022 Jun;
142(11):2853-2863.e4.
PMID: 35691364
Naked mole-rats (NMRs) (Heterocephalus glaber) are long-lived mammals that possess a natural resistance to cancer and other age-related pathologies, maintaining a healthy life span >30 years. In this study, using...
7.
Smith E, Park T, Holmes M, Buffenstein R
Adv Exp Med Biol
. 2021 Aug;
1319:409-420.
PMID: 34424527
The naked mole-rat is a species of growing research interest. Recent focus on this species from both a biomedical and zoological perspective has led to important discoveries regarding eusociality and...
8.
Hadi F, Smith E, Khaled W
Adv Exp Med Biol
. 2021 Aug;
1319:341-352.
PMID: 34424524
It is widely accepted that cancer is driven by genetic mutations that confer uncontrolled cell proliferation and tumor formation. For tumors to take hold and grow, cancer cells evolve mechanisms...
9.
Park T, Smith E, Reznick J, Bennett N, Applegate D, Larson J, et al.
Adv Exp Med Biol
. 2021 Aug;
1319:255-269.
PMID: 34424519
Naked mole-rats are extremely tolerant to low concentrations of oxygen (hypoxia) and high concentrations of carbon dioxide (hypercapnia), which is consistent with the environment that they inhabit. Naked mole-rats combine...
10.
Lewin G, Smith E, Reznick J, Debus K, Barker A, Park T
Adv Exp Med Biol
. 2021 Aug;
1319:197-220.
PMID: 34424517
The naked mole-rat (Heterocephalus glaber) is famous for its longevity and unusual physiology. This eusocial species that lives in highly ordered and hierarchical colonies with a single breeding queen, also...