Eve Kandyba
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Explore the profile of Eve Kandyba including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
395
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Recent Articles
1.
Li Y, Kandyba E, Halliwill K, Delrosario R, Tran Q, Bayani N, et al.
Cancer Discov
. 2025 Mar;
PMID: 40073432
Historical studies performed nearly a century ago using mouse skin models identified two key steps in cancer evolution: initiation, a likely mutational event, and promotion, driven by inflammation and cell...
2.
Taylor M, Kandyba E, Halliwill K, Delrosario R, Khoroshkin M, Goodarzi H, et al.
Science
. 2024 May;
384(6699):eadi7453.
PMID: 38815020
Stem cells play a critical role in cancer development by contributing to cell heterogeneity, lineage plasticity, and drug resistance. We created gene expression networks from hundreds of mouse tissue samples...
3.
Taylor M, Kandyba E, Halliwill K, Delrosario R, Koroshkin M, Goodarzi H, et al.
bioRxiv
. 2023 May;
PMID: 37215032
Adult mammalian stem cells play critical roles in normal tissue homeostasis, as well as in tumor development, by contributing to cell heterogeneity, plasticity, and development of drug resistance. The relationship...
4.
Reeves M, Kandyba E, Harris S, Del Rosario R, Balmain A
Nat Cell Biol
. 2018 May;
20(6):699-709.
PMID: 29802408
Tumour cells are subjected to evolutionary selection pressures during progression from initiation to metastasis. We analysed the clonal evolution of squamous skin carcinomas induced by DMBA/TPA treatment using the K5CreER-Confetti...
5.
Lee P, Gund R, Dutta A, Pincha N, Rana I, Ghosh S, et al.
Elife
. 2017 Dec;
6.
PMID: 29199946
The cutaneous wound-healing program is a product of a complex interplay among diverse cell types within the skin. One fundamental process that is mediated by these reciprocal interactions is the...
6.
Huang P, Kandyba E, Jabouille A, Sjolund J, Kumar A, Halliwill K, et al.
Nat Genet
. 2017 Sep;
49(11):1624-1632.
PMID: 28945253
The G-protein-coupled receptors LGR4, LGR5 and LGR6 are Wnt signaling mediators, but their functions in squamous cell carcinoma (SCC) are unclear. Using lineage tracing in Lgr5-EGFP-CreERT2/Rosa26-Tomato and Lgr6-EGFP-CreERT2/Rosa26-Tomato reporter mice,...
7.
Wang Q, Oh J, Lee H, Dhar A, Peng T, Ramos R, et al.
Elife
. 2017 Jul;
6.
PMID: 28695824
The control principles behind robust cyclic regeneration of hair follicles (HFs) remain unclear. Using multi-scale modeling, we show that coupling inhibitors and activators with physical growth of HFs is sufficient...
8.
Quigley D, Kandyba E, Huang P, Halliwill K, Sjolund J, Pelorosso F, et al.
Cell Rep
. 2016 Jul;
16(4):1153-1165.
PMID: 27425619
Inherited germline polymorphisms can cause gene expression levels in normal tissues to differ substantially between individuals. We present an analysis of the genetic architecture of normal adult skin from 470...
9.
Leung Y, Kandyba E, Chen Y, Ruffins S, Chuong C, Kobielak K
Proc Natl Acad Sci U S A
. 2014 Oct;
111(42):15114-9.
PMID: 25277970
Regulation of adult stem cells (SCs) is fundamental for organ maintenance and tissue regeneration. On the body surface, different ectodermal organs exhibit distinctive modes of regeneration and the dynamics of...
10.
Defining the localization and molecular characteristic of minor salivary gland label-retaining cells
Zhang H, Boddupally K, Kandyba E, Kobielak K, Chen Y, Zu S, et al.
Stem Cells
. 2014 Apr;
32(8):2267-77.
PMID: 24715701
Adult stem cells (SCs) are important to maintain homeostasis of tissues including several mini-organs like hair follicles and sweat glands. However, the existence of stem cells in minor salivary glands...