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Evan P Booy

Explore the profile of Evan P Booy including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 659
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Recent Articles
1.
Koul A, Gemmill D, Lubna N, Meier M, Krahn N, Booy E, et al.
Biophys J . 2025 Mar; PMID: 40086432
No abstract available.
2.
Gussakovsky D, Black N, Booy E, McKenna S
RNA Biol . 2024 Nov; 21(1):1-12. PMID: 39563162
SRP9/SRP14 is a protein heterodimer that plays a critical role in the signal recognition particle through its interaction with the scaffolding signal recognition particle RNA (7SL). SRP9/SRP14 binding to 7SL...
3.
Booy E, Gussakovsky D, Brown M, Shwaluk R, Nachtigal M, McKenna S
RNA . 2024 Aug; 30(11):1477-1494. PMID: 39179355
The noncoding RNA BC200 is elevated in human cancers and is implicated in translation regulation as well as cell survival and proliferation. Upon BC200 overexpression, we observed correlated expression of...
4.
Gussakovsky D, Booy E, Brown M, McKenna S
RNA . 2023 May; 29(8):1185-1200. PMID: 37156570
The SRP9/SRP14 heterodimer is a central component of signal recognition particle (SRP) RNA (7SL) processing and Alu retrotransposition. In this study, we sought to establish the role of nuclear SRP9/SRP14...
5.
Booy E, Gussakovsky D, Choi T, McKenna S
J Biol Chem . 2021 Jan; 296:100036. PMID: 33410401
BC200 is a noncoding RNA elevated in a broad spectrum of tumor cells that is critical for cell viability, invasion, and migration. Overexpression studies have implicated BC200 and the rodent...
6.
Koul A, Gemmill D, Lubna N, Meier M, Krahn N, Booy E, et al.
Biophys J . 2020 May; 118(11):2726-2740. PMID: 32413313
Oligoadenylate synthetases (OASs) are a family of interferon-inducible enzymes that require double-stranded RNA (dsRNA) as a cofactor. Upon binding dsRNA, OAS undergoes a conformational change and is activated to polymerize...
7.
McRae E, Dupas S, Booy E, Piragasam R, Fahlman R, McKenna S
RNA . 2019 Oct; 26(1):44-57. PMID: 31653714
DDX21 is a newly discovered RNA G-quadruplex (rG4) binding protein with no known biological rG4 targets. In this study we used label-free proteomic MS/MS to identify 26 proteins that are...
8.
Koul A, Deo S, Booy E, Orriss G, Genung M, McKenna S
Biochem Cell Biol . 2019 Apr; 98(1):70-82. PMID: 30965010
Human 2'-5' oligoadenylate synthetases (OAS) are a family of interferon-inducible proteins that, upon activation by double-stranded RNA, polymerize ATP into 2'-5' linked oligoadenylates. In this study, we probed the RNA...
9.
Booy E, McRae E, Ezzati P, Choi T, Gussakovsky D, McKenna S
Nucleic Acids Res . 2018 Sep; 46(21):11575-11591. PMID: 30247708
BC200 is a long non-coding RNA primarily expressed in brain but aberrantly expressed in various cancers. To gain a further understanding of the function of BC200, we performed proteomic analyses...
10.
Meier M, Moya-Torres A, Krahn N, McDougall M, Orriss G, McRae E, et al.
Nucleic Acids Res . 2018 May; 46(10):5319-5331. PMID: 29718405
The identification of four-stranded G-quadruplexes (G4s) has highlighted the fact that DNA has additional spatial organisations at its disposal other than double-stranded helices. Recently, it became clear that the formation...