Eva M Palsson-McDermott
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Explore the profile of Eva M Palsson-McDermott including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Zotta A, Toller-Kawahisa J, Palsson-McDermott E, OCarroll S, Henry O, Day E, et al.
Sci Adv
. 2025 Jan;
11(4):eadq7307.
PMID: 39841829
The cytokine interleukin-10 (IL-10) limits the immune response and promotes resolution of acute inflammation. Because of its immunosuppressive effects, IL-10 up-regulation is a common feature of tumor progression and metastasis....
2.
Yin M, Wadhwa R, Marshall J, Gillis C, Kim R, Dua K, et al.
J Immunol
. 2023 Nov;
212(1):13-23.
PMID: 37991425
4-Octyl itaconate (4-OI) is a derivative of the Krebs cycle-derived metabolite itaconate and displays an array of antimicrobial and anti-inflammatory properties through modifying cysteine residues within protein targets. We have...
3.
Palsson-McDermott E, ONeill L
Cell Res
. 2020 Mar;
30(4):300-314.
PMID: 32132672
The growing field of immunometabolism has taught us how metabolic cellular reactions and processes not only provide a means to generate ATP and biosynthetic precursors, but are also a way...
4.
Zaslona Z, Flis E, Wilk M, Carroll R, Palsson-McDermott E, Hughes M, et al.
Nat Commun
. 2020 Feb;
11(1):1055.
PMID: 32103022
Activated caspase-1 and caspase-11 induce inflammatory cell death in a process termed pyroptosis. Here we show that Prostaglandin E (PGE) inhibits caspase-11-dependent pyroptosis in murine and human macrophages. PGE suppreses...
5.
Angiari S, Runtsch M, Sutton C, Palsson-McDermott E, Kelly B, Rana N, et al.
Cell Metab
. 2019 Nov;
31(2):391-405.e8.
PMID: 31761564
Pyruvate kinase (PK) catalyzes the conversion of phosphoenolpyruvate to pyruvate during glycolysis. The PK isoform PKM2 has additional roles in regulation of gene transcription and protein phosphorylation. PKM2 has been...
6.
Hughes M, Hooftman A, Angiari S, Tummala P, Zaslona Z, Runtsch M, et al.
Cell Rep
. 2019 Oct;
29(1):151-161.e5.
PMID: 31577945
The NLRP3 inflammasome is a cytosolic complex sensing phagocytosed material and various damage-associated molecular patterns, triggering production of the pro-inflammatory cytokines interleukin-1 beta (IL)-1β and IL-18 and promoting pyroptosis. Here,...
7.
McElvaney O, Zaslona Z, Becker-Flegler K, Palsson-McDermott E, Boland F, Gunaratnam C, et al.
Am J Respir Crit Care Med
. 2019 Aug;
200(11):1381-1391.
PMID: 31454256
Cystic fibrosis (CF) pulmonary disease is characterized by chronic infection with and sustained neutrophil-dominant inflammation. The lack of effective antiinflammatory therapies for people with CF (PWCF) represents a significant challenge....
8.
Early J, Menon D, Wyse C, Cervantes-Silva M, Zaslona Z, Carroll R, et al.
Proc Natl Acad Sci U S A
. 2018 Aug;
115(36):E8460-E8468.
PMID: 30127006
A variety of innate immune responses and functions are dependent on time of day, and many inflammatory conditions are associated with dysfunctional molecular clocks within immune cells. However, the functional...
9.
Diskin C, Palsson-McDermott E
Front Immunol
. 2018 Mar;
9:270.
PMID: 29520272
Traditionally cellular respiration or metabolism has been viewed as catabolic and anabolic pathways generating energy and biosynthetic precursors required for growth and general cellular maintenance. However, growing literature provides evidence...
10.
Palsson-McDermott E, Curtis A, Goel G, Lauterbach M, Sheedy F, Gleeson L, et al.
Cell Metab
. 2018 Mar;
21(2):347.
PMID: 29510100
No abstract available.