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Eun A Ko

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Articles 39
Citations 793
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Recent Articles
1.
Park B, Lee K, Park K, Park H, Ko E, Lee J, et al.
Bone Joint Res . 2025 Mar; 14(3):236-244. PMID: 40081414
Aims: It remains unclear which factors influence overgrowth of the tibia, resulting from the metaphyseal hole created during anterior cruciate ligament (ACL) reconstruction in skeletally immature patients. This study aimed...
2.
Pritchard H, Gonzales A, Pires P, Drumm B, Ko E, Sanders K, et al.
Sci Signal . 2017 Sep; 10(497). PMID: 28928237
Junctional membrane complexes facilitate excitation-contraction coupling in skeletal and cardiac muscle cells by forming subcellular invaginations that maintain close (≤20 nm) proximity of ryanodine receptors (RyRs) on the sarcoplasmic reticulum...
3.
Wang R, Gurguis C, Gu W, Ko E, Lim I, Bang H, et al.
Sci Rep . 2015 Aug; 5:11593. PMID: 26235283
Ion channels are important regulators in cell proliferation, migration, and apoptosis. The malfunction and/or aberrant expression of ion channels may disrupt these important biological processes and influence cancer progression. In...
4.
Yamamura H, Yamamura A, Ko E, Pohl N, Smith K, Zeifman A, et al.
Am J Physiol Cell Physiol . 2014 Feb; 306(9):C871-8. PMID: 24573085
Notch signaling plays a critical role in controlling proliferation and differentiation of pulmonary arterial smooth muscle cells (PASMC). Upregulated Notch ligands and Notch3 receptors in PASMC have been reported to...
5.
Ko J, Gu W, Lim I, Bang H, Ko E, Zhou T
PLoS One . 2014 Jan; 9(1):e86569. PMID: 24466154
Ion channels are known to regulate cancer processes at all stages. The roles of ion channels in cancer pathology are extremely diverse. We systematically analyzed the expression patterns of ion...
6.
Ko J, Ko E, Gu W, Lim I, Bang H, Zhou T
Mol Cancer . 2013 Sep; 12(1):106. PMID: 24053408
Background: Ion channels play a critical role in a wide variety of biological processes, including the development of human cancer. However, the overall impact of ion channels on tumorigenicity in...
7.
Yoo H, Zeifman A, Ko E, Smith K, Chen J, Machado R, et al.
Pulm Circ . 2013 Sep; 3(2):396-405. PMID: 24015341
Hypoxic pulmonary vasoconstriction (HPV) is a compensatory physiological mechanism in the lung that optimizes the matching of ventilation to perfusion and thereby maximizes gas exchange. Historically, HPV has been primarily...
8.
Wan J, Yamamura A, Zimnicka A, Voiriot G, Smith K, Tang H, et al.
Am J Physiol Lung Cell Mol Physiol . 2013 May; 305(2):L154-64. PMID: 23686856
Hypoxia-induced pulmonary hypertension (HPH) is characterized by sustained pulmonary vasoconstriction and vascular remodeling, both of which are mediated by pulmonary artery smooth muscle cell (PASMC) contraction and proliferation, respectively. An...
9.
Ko E, Wan J, Yamamura A, Zimnicka A, Yamamura H, Yoo H, et al.
Am J Physiol Cell Physiol . 2013 Feb; 304(11):C1042-52. PMID: 23426966
Electromechanical coupling via membrane depolarization-mediated activation of voltage-dependent Ca(2+) channels (VDCC) is an important mechanism in regulating pulmonary vascular tone, while mouse is an animal model often used to study...
10.
Yamamura A, Yamamura H, Guo Q, Zimnicka A, Wan J, Ko E, et al.
Circ Res . 2013 Jan; 112(4):640-50. PMID: 23300272
Rationale: An increase in cytosolic free Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for PASMC proliferation...