Eugene Tulchinsky
Overview
Explore the profile of Eugene Tulchinsky including associated specialties, affiliations and a list of published articles.
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32
Citations
1810
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Recent Articles
1.
Malikova I, Worth A, Aliyeva D, Khassenova M, Kriajevska M, Tulchinsky E
Cell Death Dis
. 2025 Mar;
16(1):155.
PMID: 40044635
Proteolytic processing of Receptor Tyrosine Kinases (RTKs) leads to the release of ectodomains in the extracellular space. These soluble ectodomains often retain the ligand binding activity and dampen canonical pathways...
2.
Terragno M, Vetrova A, Semenov O, Sayan A, Kriajevska M, Tulchinsky E
Sci Rep
. 2024 Jan;
14(1):425.
PMID: 38172210
Triple-negative breast cancer (TNBC) is a difficult-to-treat, aggressive cancer type. TNBC is often associated with the cellular program of epithelial-mesenchymal transition (EMT) that confers drug resistance and metastasis. EMT and...
3.
EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?
Akhmetkaliyev A, Alibrahim N, Shafiee D, Tulchinsky E
Mol Cancer
. 2023 May;
22(1):90.
PMID: 37259089
Epithelial mesenchymal transition (EMT) and mesenchymal epithelial transition (MET) are genetic determinants of cellular plasticity. These programs operate in physiological (embryonic development, wound healing) and pathological (organ fibrosis, cancer) conditions....
4.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, et al.
Nat Cancer
. 2022 Feb;
1(7):750.
PMID: 35122045
No abstract available.
5.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, et al.
Nat Cancer
. 2022 Feb;
1(6):620-634.
PMID: 35121975
Colorectal cancer (CRC) is highly prevalent in Western society, and increasing evidence indicates strong contributions of environmental factors and the intestinal microbiota to CRC initiation, progression and even metastasis. We...
6.
Auyez A, Sayan A, Kriajevska M, Tulchinsky E
Cancers (Basel)
. 2021 Oct;
13(19).
PMID: 34638349
The TAM proteins TYRO3, AXL, and MER are receptor tyrosine kinases implicated in the clearance of apoptotic debris and negative regulation of innate immune responses. AXL contributes to immunosuppression by...
7.
Sreekumar R, Al-Saihati H, Emaduddin M, Moutasim K, Mellone M, Patel A, et al.
Mol Oncol
. 2021 May;
15(8):2065-2083.
PMID: 33931939
Resistance to adjuvant chemotherapy is a major clinical problem in the treatment of colorectal cancer (CRC). The aim of this study was to elucidate the role of an epithelial to...
8.
Sreekumar R, Emaduddin M, Al-Saihati H, Moutasim K, Chan J, Spampinato M, et al.
Cell Death Dis
. 2019 Sep;
10(10):703.
PMID: 31543517
Epithelial-mesenchymal transition (EMT) is a process by which tumour cells lose epithelial characteristics, become mesenchymal and highly motile. EMT pathways also induce stem cell features and resistance to apoptosis. Identifying...
9.
Al-Ismaeel Q, Neal C, Al-Mahmoodi H, Almutairi Z, Al-Shamarti I, Straatman K, et al.
Br J Cancer
. 2019 May;
121(1):65-75.
PMID: 31123345
Background: S100 proteins have been implicated in various aspects of cancer, including epithelial-mesenchymal transitions (EMT), invasion and metastasis, and also in inflammatory disorders. Here we examined the impact of individual...
10.
Li N, Babaei-Jadidi R, Lorenzi F, Spencer-Dene B, Clarke P, Domingo E, et al.
Oncogenesis
. 2019 Feb;
8(3):13.
PMID: 30783098
Colorectal cancer (CRC) patients develop recurrence after chemotherapy owing to the survival of stem cell-like cells referred to as cancer stem-like cells (CSCs). The origin of CSCs is linked to...