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Ethan Harris

Explore the profile of Ethan Harris including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 85
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Recent Articles
1.
Jin Q, Harris E, Myers J, Mehmood R, Cotton A, Shirnekhi H, et al.
Blood . 2024 Sep; 144(23):2417-2431. PMID: 39316649
There are only a few options for patients with relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL), thus, this is a major area of unmet medical need. In this study, we reveal...
2.
Harris E, Thawani R
Curr Probl Cancer . 2024 Jun; 51:101106. PMID: 38879917
NSCLC has a diverse genomic background with mutations in key proto-oncogenic drivers including Kirsten rat sarcoma (KRAS) and epidermal growth factor receptor (EGFR). Roughly 40% of adenocarcinoma harbor Kras activating...
3.
Stoler-Barak L, Harris E, Peres A, Hezroni H, Kuka M, Di Lucia P, et al.
Nat Commun . 2023 Mar; 14(1):1462. PMID: 36927854
Protection from viral infections depends on immunoglobulin isotype switching, which endows antibodies with effector functions. Here, we find that the protein kinase DYRK1A is essential for B cell-mediated protection from...
4.
Huang J, Harris E, Lorch J
Oral Oncol . 2022 Nov; 135:106083. PMID: 36332445
Patients with recurrent or metastatic NPC are left with limited treatment options. The close association between EBV and NPC make therapeutic vaccination targeting EBV-antigens an emerging new treatment modality. Therapeutic...
5.
Rammohan M, Harris E, Bhansali R, Zhao E, Li L, Crispino J
Oncogene . 2022 Feb; 41(14):2003-2011. PMID: 35220406
Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) is a serine/threonine kinase that belongs to the DYRK family of proteins, a subgroup of the evolutionarily conserved CMGC protein kinase superfamily. Due...
6.
Ford B, Dore M, Harris E
Am Fam Physician . 2021 Sep; 104(3):316-320. PMID: 34523900
No abstract available.
7.
Harris E, Mihai D, Hare J
Neural Comput . 2021 Jan; 33(4):858-898. PMID: 33400902
Recent work suggests that changing convolutional neural network (CNN) architecture by introducing a bottleneck in the second layer can yield changes in learned function. To understand this relationship fully requires...
8.
Bhansali R, Rammohan M, Lee P, Laurent A, Wen Q, Suraneni P, et al.
J Clin Invest . 2021 Jan; 131(1). PMID: 33393494
DYRK1A is a serine/threonine kinase encoded on human chromosome 21 (HSA21) that has been implicated in several pathologies of Down syndrome (DS), including cognitive deficits and Alzheimer's disease. Although children...
9.
Arthur A, Bellile E, Rozek L, Peterson K, Ren J, Harris E, et al.
Head Neck . 2015 Nov; 38 Suppl 1:E1591-7. PMID: 26614223
Background: The purpose of this study was to examine associations of pretreatment serum carotenoids, tocopherols, and quercetin with prognosis in 154 patients newly diagnosed with head and neck cancer. Methods:...
10.
Xue Y, Harris E, Wang W, Baybutt R
J Biomed Sci . 2015 Oct; 22:84. PMID: 26462767
Background: We have previously demonstrated that cigarette smoke is associated with a significant reduction of retinoic acid in rat lungs and the formation of tracheal precancerous lesions. However, the underlying...