Bon Ham Yip
Overview
Explore the profile of Bon Ham Yip including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
430
Followers
0
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Recent Articles
1.
Stoler-Barak L, Harris E, Peres A, Hezroni H, Kuka M, Di Lucia P, et al.
Nat Commun
. 2023 Mar;
14(1):1462.
PMID: 36927854
Protection from viral infections depends on immunoglobulin isotype switching, which endows antibodies with effector functions. Here, we find that the protein kinase DYRK1A is essential for B cell-mediated protection from...
2.
Bhansali R, Rammohan M, Lee P, Laurent A, Wen Q, Suraneni P, et al.
J Clin Invest
. 2021 Jan;
131(1).
PMID: 33393494
DYRK1A is a serine/threonine kinase encoded on human chromosome 21 (HSA21) that has been implicated in several pathologies of Down syndrome (DS), including cognitive deficits and Alzheimer's disease. Although children...
3.
Yip B
Biomolecules
. 2020 Jun;
10(6).
PMID: 32486234
The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has revolutionized the field of gene editing. Continuous efforts in developing this technology have enabled efficient in vitro, ex vivo, and...
4.
Bauler M, Roberts J, Wu C, Fan B, Ferrara F, Yip B, et al.
Mol Ther Methods Clin Dev
. 2020 Jan;
17:58-68.
PMID: 31890741
Lentiviral vectors are increasingly utilized in cell and gene therapy applications because they efficiently transduce target cells such as hematopoietic stem cells and T cells. Large-scale production of current Good...
5.
Chase A, Pellagatti A, Singh S, Score J, Tapper W, Lin F, et al.
Leukemia
. 2018 Dec;
33(5):1184-1194.
PMID: 30573780
Acquired uniparental disomy (aUPD, also known as copy-neutral loss of heterozygosity) is a common feature of cancer cells and characterized by extended tracts of somatically-acquired homozygosity without any concurrent loss...
6.
Bello E, Kerry J, Singh S, Yip B, Kusec R, Killick S, et al.
Haematologica
. 2018 Jun;
103(11):e496-e500.
PMID: 29903759
No abstract available.
7.
Yip B, Steeples V, Repapi E, Armstrong R, Llorian M, Roy S, et al.
J Clin Invest
. 2017 Sep;
127(9):3557.
PMID: 28862641
No abstract available.
8.
Yip B, Tsai C, Rane J, Vetharoy W, Anguita E, Dong S, et al.
Haematologica
. 2017 May;
102(8):e300-e304.
PMID: 28522575
No abstract available.
9.
Yip B, Steeples V, Repapi E, Armstrong R, Llorian M, Roy S, et al.
J Clin Invest
. 2017 Apr;
127(6):2206-2221.
PMID: 28436936
Mutations of the splicing factor-encoding gene U2AF1 are frequent in the myelodysplastic syndromes (MDS), a myeloid malignancy, and other cancers. Patients with MDS suffer from peripheral blood cytopenias, including anemia,...
10.
Yip B, Dolatshad H, Roy S, Pellagatti A, Boultwood J
Curr Pharm Des
. 2016 Feb;
22(16):2333-44.
PMID: 26916023
Splicing is an essential cellular process which is carried out by the spliceosome in order to remove the introns and join the exons present in pre-mRNA transcripts. A variety of...